Long term use of eltrombopag in children with chronic immune thrombocytopenia: extended real life retrospective multicenter experience of the Italian Association of Pediatric Hematology and Oncology.

Author: BaroneAngelica, CesaroSimone, Del VecchioGiovanni Carlo, FotziIlaria, GionaFiorina, GiordanoPaola, GorioChiara, LassandroGiuseppe, MaggioAngela, MarzolloAntonio, MianoMaurizio, NardiMargherita, PalladinoValentina, PessionAndrea, RuggieroAntonio, RussoGiovanna, SaraccoPaola, SpinelliMarco, TolvaAlessandra, TorneselloAssunta

Paper Details 
Original Abstract of the Article :
BACKGROUND: The present multicenter retrospective study on eltrombopag administration in Italian children with chronic ITP aims to extend follow-up of our previous study. MATERIALS AND METHODS: This retrospective multicenter study was conducted in 17 centers affiliated to the Italian Association of...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375288/

データ提供:米国国立医学図書館(NLM)

Long-Term Eltrombopag Treatment in Children with ITP

This research investigates the long-term use of eltrombopag, a medication used to treat chronic immune thrombocytopenia (ITP), in children. The study analyzed data from a multi-center retrospective study involving 56 children with ITP who received eltrombopag treatment for a median duration of 40 months. The study aimed to extend the follow-up period from a previous study and evaluate the long-term safety and efficacy of eltrombopag. The results showed that while eltrombopag treatment was effective in improving platelet count and reducing the need for other therapies, a significant number of patients discontinued treatment due to adverse effects or ineffectiveness.

Eltrombopag: A Double-Edged Sword

The study, like a desert traveler who carefully weighs the risks and benefits of each step, highlights the need for ongoing monitoring and personalized treatment approaches when using eltrombopag in children with ITP.

Navigating ITP Treatment

It is important to weigh the benefits and risks of eltrombopag treatment for children with ITP, and to closely monitor patients for any potential side effects.

Dr.Camel's Conclusion

This study underscores the importance of carefully considering the long-term implications of eltrombopag treatment for children with ITP and emphasizes the need for ongoing research and monitoring to optimize treatment strategies.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-08-01
Further Info :

Pubmed ID

37521342

DOI: Digital Object Identifier

PMC10375288

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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