Interaction Between Determinants Governing Urine Volume in Patients With ADPKD on Tolvaptan and its Impact on Quality of Life.

Author: ArjuneSita, BenzingThomas, BoehmVolker, BurkertKatharina, BurstVolker Rolf, GrundmannFranziska, HendrixClaudia, KraußDenise, MüllerRoman-Ulrich, OehmSimon, SchmidtJohannes, TodorovaPolina

Paper Details 
Original Abstract of the Article :
Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent genetic cause of kidney failure. Tolvaptan, a vasopressin 2 receptor antagonist, is the first drug with proven disease-modifying activity. Long-term treatment adherence is crucial, but a considerable fraction of patients disc...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403673/

データ提供:米国国立医学図書館(NLM)

Tolvaptan and ADPKD: A Camel's Journey Through the Desert of Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD), a genetic disorder affecting the kidneys, is like a slow-moving sandstorm that gradually erodes kidney function. This research explores the impact of tolvaptan, a vasopressin 2 receptor antagonist, on urine volume and quality of life in patients with ADPKD. The study found that tolvaptan, while effective in reducing cyst growth, can lead to significant aquaretic side effects, such as increased urination, which can negatively impact patient adherence to treatment.

Navigating the Challenges of ADPKD Treatment: A Camel's Perspective

This study highlights the complex interplay between treatment efficacy and patient quality of life in ADPKD. Finding the right balance between managing disease progression and mitigating side effects is crucial for ensuring optimal patient outcomes. It's like navigating a desert with limited water sources, where careful planning and resource management are essential for survival.

A Camel's Advice for Managing ADPKD

Managing ADPKD requires a collaborative approach between patients and healthcare professionals. Understanding the potential side effects of treatment and developing strategies to mitigate their impact are essential for improving patient adherence and quality of life.

Dr.Camel's Conclusion

This study underscores the importance of addressing the side effects of tolvaptan in patients with ADPKD. Finding ways to optimize treatment strategies to improve patient adherence and quality of life is an ongoing journey. It's a reminder that the quest for better treatments for chronic conditions, like ADPKD, requires a focus on both efficacy and patient well-being.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-08-08
Further Info :

Pubmed ID

37547529

DOI: Digital Object Identifier

PMC10403673

Related Literature

SNS
PICO Info
in preparation
Languages

English

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