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18-Month efficacy and safety analysis of monthly subcutaneous buprenorphine injection for opioid use disorder: Integrated analysis of phase 3 studies.

Author: BoyettBrent, HassmanDavid, LearnedSusan M, RutrickDaniel, ShindeSunita, ZhaoYue

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study evaluated the long-term efficacy, safety, and tolerability of monthly extended-release buprenorphine (BUP-XR) in participants seeking treatment for opioid use disorder (OUD). The study was conducted via an integrated analysis of phase 3 studies.
Paper Details　
Original Abstract of the Article :
Few studies investigate the natural history of patients on long-term treatment for opioid use disorder (OUD). We evaluated the long-term efficacy, safety, and tolerability experience of monthly extended-release buprenorphine (BUP-XR) in participants seeking treatment for OUD, via integrated analysis...See full text at original site
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引用元：
https://doi.org/10.1016/j.josat.2023.209155

データ提供：米国国立医学図書館（NLM）

Long-Term Buprenorphine: A Oasis in the Desert of Opioid Use Disorder

Opioid use disorder (OUD) is a complex and challenging condition, often requiring long-term treatment to manage cravings and prevent relapse. This research investigates the long-term efficacy, safety, and tolerability of monthly extended-release buprenorphine (BUP-XR) in patients seeking treatment for OUD. The authors sought to understand the long-term impact of this medication, providing valuable insights for healthcare providers and patients navigating the complexities of OUD treatment.

The authors recognize the need for effective and safe long-term treatment options for OUD, seeking to provide sustained support for those struggling with this condition. Their research is like a camel venturing into a challenging desert, seeking a sustainable source of water and sustenance for those seeking recovery.

A Beacon of Hope: Sustained Support for Recovery

The authors' integrated analysis of phase 3 studies revealed that monthly BUP-XR demonstrated long-term efficacy and safety, offering a potential solution for managing OUD. This research provides a glimmer of hope for those seeking long-term recovery, offering a potential oasis in the desert of opioid use disorder.

A Guide for Treatment: Navigating the Path to Recovery

The authors' findings provide valuable insights for healthcare providers, guiding them in the use of BUP-XR for the long-term management of OUD. This research offers a roadmap for navigating the complexities of OUD treatment, emphasizing the importance of sustained support and individualized care plans.

Dr. Camel's Conclusion

This research provides valuable insights into the long-term efficacy, safety, and tolerability of monthly extended-release buprenorphine for opioid use disorder. The findings highlight the potential of this medication as a sustainable solution for managing this complex condition, offering hope for patients seeking long-term recovery.

Date :
  1. Date Completed 2023-10-02
  2. Date Revised 2023-10-12
Further Info :

Pubmed ID

37657559

DOI: Digital Object Identifier

10.1016/j.josat.2023.209155

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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