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Effects of rivaroxaban on myocardial mitophagy in the rat heart.

Author: AkokayPinar, BayrakSerdar, BilenCagatay, ErdalCenk, GencpinarTugra, KacarKivanc, KemahliBaris

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Rivaroxaban may have reduced cell death in cardiomyocytes during myocardial infarction and thus have reduced damage to the heart tissue caused by myocardial infarction.
Paper Details　
Original Abstract of the Article :
BACKGROUND: This study aims to demonstrate the efficacy of rivaroxaban's pharmacokinetic effects on myocardial mitophagy in rats by inducing apoptosis. METHODS: In this double-blind experiment, Wistar albino male rats were randomly divided into three groups for an experimental ischemia model: the s...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472476/

データ提供：米国国立医学図書館（NLM）

Rivaroxaban: A Potential Protector Against Myocardial Mitophagy?

Myocardial infarction, a life-threatening condition, results from the sudden blockage of blood flow to the heart, often leading to tissue damage and cell death. This study explores the impact of rivaroxaban, an anticoagulant medication, on myocardial mitophagy, a process that removes damaged mitochondria from heart cells.

The researchers investigated the effects of rivaroxaban on myocardial mitophagy in a rat model of ischemia-reperfusion injury, a common cause of myocardial infarction. They found that rivaroxaban treatment reduced the activation of apoptosis pathways, indicating a potential protective effect against cell death.

Rivaroxaban: A Potential New Ally in the Fight Against Myocardial Infarction

This study, like a beacon of hope in a vast desert of cardiac research, suggests that rivaroxaban may play a protective role in myocardial infarction. The findings indicate that rivaroxaban may help mitigate the damage caused by ischemia-reperfusion injury, potentially improving heart function and reducing the risk of complications.

Protecting Your Heart: A Journey of Prevention and Treatment

This research highlights the importance of exploring new therapeutic strategies to combat myocardial infarction. The findings suggest that rivaroxaban, in addition to its established anticoagulant properties, may offer additional benefits in protecting the heart from damage during ischemic events.

Dr.Camel's Conclusion

This study, like a refreshing oasis in a desert of cardiac research, offers hope for those battling myocardial infarction. The findings suggest that rivaroxaban, a medication commonly used to prevent blood clots, may also play a protective role in reducing heart damage during ischemic events. The research encourages further investigation into the potential therapeutic benefits of rivaroxaban, offering the possibility of new treatment strategies to combat this life-threatening condition.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-09-05
Further Info :

Pubmed ID

37664781

DOI: Digital Object Identifier

PMC10472476

Related Literature

Article Analysis
・Effects of rivaroxaban
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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