Paper Details 
Original Abstract of the Article :
Trifluridine/tipiracil plus VEGF inhibition with ramucirumab (RAM) for advanced gastric cancer (AGC) demonstrated clinical activity with an acceptable toxicity profile in previous phase II trial. However, little is known about its efficacy and safety in clinical practice in comparison with triflurid...See full text at original site
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引用元:
https://doi.org/10.1007/s10120-023-01427-9

データ提供:米国国立医学図書館(NLM)

Trifluridine/Tipiracil Plus Ramucirumab: A New Oasis in the Desert of Gastric Cancer

Gastric cancer is a formidable disease, often presenting with advanced stages that require aggressive treatment. This study investigated the efficacy and safety of trifluridine/tipiracil plus ramucirumab (RAM) in comparison to trifluridine/tipiracil monotherapy for patients with advanced gastric cancer. The authors sought to evaluate the clinical activity and toxicity profile of this combination therapy.

A New Treatment Landscape for Gastric Cancer: Navigating the Desert of Advanced Disease

The study found that the combination of trifluridine/tipiracil plus ramucirumab demonstrated clinical activity and an acceptable toxicity profile. This finding suggests that this combination therapy may offer a promising new treatment option for patients with advanced gastric cancer, particularly in situations where monotherapy has failed or is not suitable.

Finding Hope in the Desert of Treatment Options

The study underscores the importance of personalized treatment approaches for patients with gastric cancer, considering the unique characteristics of each individual. By exploring new combination therapies and evaluating their efficacy and safety profiles, we can expand the options available for patients and improve their chances of survival and quality of life.

Dr.Camel's Conclusion

The desert of gastric cancer can be a daunting and unforgiving place, but with the development of new therapies like trifluridine/tipiracil plus ramucirumab, we can offer a new oasis of hope for those battling this disease. This study provides valuable insights into the potential of this combination therapy, paving the way for more effective treatment strategies and improved outcomes for patients.

Date :
  1. Date Completed 2023-11-13
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

37665515

DOI: Digital Object Identifier

10.1007/s10120-023-01427-9

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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