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Maternal chronic caffeine intake impairs fertility, placental vascularization and fetal development in mice.

Author: BloiseEnrrico, Caldeira-BrantAndre Lucas, CardosoLucas Carvalho, Castro-OliveiraHortencia, Chiarini-GarciaHelio, FelicioniFernando, MenezesGustavo Batista, PaulaThais de Merici Domingues E, SantosThais Garcia, de AlmeidaFernanda Radicchi Campos Lobato

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigated the effects of caffeine consumption during pregnancy in mice. The study found that even moderate amounts of caffeine (60 mg/kg/day) can harm placental development and lead to restricted fetal growth, particularly in female fetuses. Higher doses of caffeine (120 mg/kg/day) were associated with changes in placental blood flow and increased fetal vessel development. The study suggests that pregnant women should avoid consuming caffeine levels above recommended doses.
Paper Details　
Original Abstract of the Article :
Caffeine is commonly consumed by pregnant women to avoid fatigue or as a habit. However, it is not clearly determined its side effects to the conceptuses. This study evaluated placental morphofunctional alterations after maternal chronic caffeine intake and the effects on fetal growth. Female Swiss ...See full text at original site
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引用元：
https://doi.org/10.1016/j.reprotox.2023.108471

データ提供：米国国立医学図書館（NLM）

Caffeine: A Potential Sandstorm in the Desert of Pregnancy

Pregnancy is a delicate journey, requiring careful attention to both maternal and fetal health. This research investigates the potential impact of caffeine consumption on pregnancy outcomes in mice. The authors exposed pregnant mice to varying doses of caffeine, examining its effects on placental development, fetal growth, and overall pregnancy success. Their findings provide valuable insights into the potential risks of caffeine during pregnancy, highlighting the need for caution and moderation.

Caffeine's Shadow: Potential Risks for Pregnancy

The study found that chronic caffeine intake during pregnancy can have detrimental effects on placental vascularization, fetal growth, and even fertility. [Effects of maternal chronic caffeine intake on pregnancy]. These findings suggest that caffeine consumption during pregnancy, even in moderate amounts, should be approached with caution.

A Camel's Perspective on Caffeine and Pregnancy

Imagine a camel crossing a desert, its journey guided by the wisdom of its ancestors. Pregnancy is a similar journey, requiring careful navigation to ensure the well-being of both mother and child. This research highlights the potential risks of caffeine during pregnancy, reminding us that even seemingly harmless substances can have unforeseen consequences. Just as a camel needs to be cautious about the dangers of the desert, pregnant women should be mindful of their caffeine intake and consult with their healthcare providers about appropriate levels of consumption.

Dr. Camel's Conclusion

This study suggests that chronic caffeine intake during pregnancy can have significant negative consequences for both mother and child. While further research is needed to confirm these findings in humans, it is prudent to exercise caution and moderation in caffeine consumption during pregnancy. Consulting with healthcare providers about appropriate caffeine levels can help ensure a safe and healthy pregnancy.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-10-09
Further Info :

Pubmed ID

37717671

DOI: Digital Object Identifier

10.1016/j.reprotox.2023.108471

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Languages

English

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