A single-dose strategy for immunization with live attenuated vaccines is an effective option before treatment initiation in multiple sclerosis patients.

Author: ArrambideGeorgina, BolloLuca, Borras-BemejoBlanca, BragaNathane, CarbonellPere, CarvajalRené, CastillóJoaquín, Cobo-CalvoAlvaro, ComabellaManuel, EsperalbaJuliana, GalánIngrid, Martínez-GómezXavier, MidagliaLuciana, Mongay-OchoaNeus, MontalbanXavier, Otero-RomeroSusana, PappollaAgustín, Rodrigo-PendásJosé Ángel, RodriguezMarta, Rodríguez-AcevedoBreogán, RíoJordi, Sastre-GarrigaJaume, TintoréMar, TurCarmen, Vidal-JordanaÁngela, ZabalzaAna

Paper Details 
Original Abstract of the Article :
Mumps-Measles-Rubella (MMR) and Varicella zoster vaccines (VAR) are live attenuated vaccines, usually administered in a two-dose scheme at least 4 weeks apart. However, single-dose immunization schemes may also be effective and can reduce delays in immunosuppressive treatment initiation in patients ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687797/

データ提供:米国国立医学図書館(NLM)

Multiple Sclerosis: Finding a Path Through the Desert of Immunity

Multiple sclerosis (MS), a complex and challenging autoimmune disease, affects the central nervous system, disrupting the flow of information within the body, much like a desert storm disrupting a caravan's journey. This research explores the feasibility of a single-dose vaccination strategy for individuals with MS, a potential shortcut through the desert of immunization protocols.

The researchers investigated the effectiveness of administering a single dose of live attenuated vaccines, such as MMR (measles, mumps, rubella) and VAR (varicella zoster), to individuals with MS before initiating immunosuppressive treatment. They sought to determine if a single dose could provide adequate protection while minimizing delays in treatment.

A Shortcut Through the Desert of Immunization

The study found that a single-dose vaccination strategy was effective in providing immunity against the targeted diseases, offering a potential shortcut through the traditional two-dose vaccination protocol. This strategy could be particularly beneficial for individuals with MS, who often require immediate immunosuppressive therapy, reducing the time needed to complete the vaccination regimen.

Navigating the Desert with Efficiency

This research suggests that a single-dose vaccination strategy can be a safe and effective option for individuals with MS, streamlining the immunization process and allowing for more timely initiation of treatment. It offers a potential solution to navigate the challenges of immunization protocols in individuals with complex medical conditions.

Dr. Camel's Conclusion

This research offers a promising new approach to vaccination for individuals with MS, providing a potential shortcut through the desert of immunization protocols. The findings suggest that a single-dose strategy can be equally effective in providing immunity, allowing for more efficient and timely initiation of treatment. It's a reminder that even in the face of complex medical challenges, innovation and research can pave the way for more streamlined and effective healthcare solutions.

Date :
  1. Date Completed 2023-11-30
  2. Date Revised 2023-12-01
Further Info :

Pubmed ID

37728389

DOI: Digital Object Identifier

PMC10687797

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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