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Surgery after sonidegib treatment achieves complete response in locally advanced basal cell carcinoma of the face.
Author: BocchinoE, CappilliS, Di StefaniA, ParadisiA, PerisK, PiccerilloA, RicciC
Original Abstract of the Article :
Basal cell carcinoma accounts for 75% of skin cancers worldwide and is the most common malignancy in Caucasians. Since chronic ultraviolet exposure is the major risk factor for its development, sun-exposed areas such as the face are frequently affected. The gold-standard treatment is surgical excisi...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/1346-8138.16970
データ提供:米国国立医学図書館(NLM)
Sonidegib: A New Hope for Advanced Basal Cell Carcinoma
Basal cell carcinoma, the most common type of skin cancer, often presents a challenge for treatment. This study explores the potential of sonidegib, a hedgehog pathway inhibitor, as a neoadjuvant therapy for locally advanced basal cell carcinoma of the face. The authors report two cases where sonidegib treatment followed by limited surgical excision achieved complete remission. The results suggest that sonidegib could be a valuable tool in managing advanced basal cell carcinoma, reducing tumor size and allowing for less extensive surgery.Sonidegib Offers a Less Invasive Approach to Treatment
The study highlights the potential of sonidegib as a less invasive alternative to traditional treatments for advanced basal cell carcinoma. By shrinking the tumor before surgery, sonidegib can minimize the need for extensive excision, leading to improved cosmetic outcomes and reduced scarring. This approach could be particularly beneficial for patients with lesions located in sensitive areas like the face.Protecting Your Skin: Sun Safety and Early Detection are Key
This research underscores the importance of protecting your skin from the sun’s harmful rays. Ultraviolet exposure is a major risk factor for basal cell carcinoma, so wearing sunscreen, seeking shade, and avoiding sunburns are crucial for preventing this common cancer. Early detection is also vital, as treatment is more effective when the cancer is caught in its early stages. Regular skin checks, including self-exams, can help catch any suspicious growths or changes.Dr.Camel's Conclusion
Sonidegib shows promise as a new weapon in the battle against advanced basal cell carcinoma. Its ability to reduce tumor size and allow for less invasive surgery could offer patients a better quality of life. However, further research is needed to fully understand its effectiveness and long-term implications. In the meantime, remember, sun safety and early detection are crucial for preventing and managing this common form of skin cancer.Date :
- Date Completed n.d.
- Date Revised 2023-09-21
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