Efficacy of ESHAP versus ICE plus dexamethasone (DICE) as salvage chemotherapy for relapsed or refractory diffuse large B-cell lymphoma.

Author: BoonlerdPattamaporn, Chai-AdisaksophaChatree, HantrakoolSasinee, HantrakunNonthakorn, NorasetthadaLalita, PiriyakhuntornPokpong, PunnachetTeerachat, RattanathammetheeThanawat, RattarittamrongEkarat, TantiworawitAdisak

Paper Details 
Original Abstract of the Article :
OBJECTIVES: To compare the efficacy and side effects of salvage chemotherapy between etoposide, methylprednisolone, cytarabine and cisplatin (ESHAP) and ifosfamide, carboplatin and etoposide plus dexamethasone (DICE) for relapsed or refractory diffuse large B-cell lymphoma (DLBCL). METHODS: Medical...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521335/

データ提供:米国国立医学図書館(NLM)

Comparing ESHAP and DICE Regimens for Relapsed or Refractory DLBCL

The battle against cancer is a constant struggle, and finding effective treatments for relapsed or refractory diffuse large B-cell lymphoma (DLBCL) is a crucial endeavor. This study, exploring the realm of hematology, compares the efficacy and side effects of two salvage chemotherapy regimens: ESHAP and DICE, for patients with relapsed or refractory DLBCL.

ESHAP vs. DICE: Efficacy and Side Effects

The study, conducted through a retrospective review of medical records, revealed that both ESHAP and DICE regimens demonstrated comparable efficacy in terms of two-year progression-free survival, two-year overall survival, and overall response rate. However, the DICE regimen was associated with fewer renal adverse events than ESHAP. The findings highlight the need for a personalized approach to treatment decisions, considering individual patient factors and potential side effects.

Understanding the Landscape of Cancer Treatment

This research emphasizes the importance of tailoring treatment plans based on specific patient characteristics and the potential for side effects. The study reminds us that the quest for effective and tolerable treatments for relapsed or refractory cancers continues, and ongoing research is crucial for improving outcomes for patients.

Dr.Camel's Conclusion

Think of it like a camel navigating a treacherous sandstorm. A wise camel chooses the path that offers the best chance of survival, just as a physician must carefully consider the risks and benefits of different treatment options for their patients. This research underscores the importance of ongoing research and personalized approaches to cancer treatment, in hopes of finding a clear path to a healthy destination for those facing this challenging disease.

Date :
  1. Date Completed 2023-09-27
  2. Date Revised 2023-10-09
Further Info :

Pubmed ID

37748107

DOI: Digital Object Identifier

PMC10521335

Related Literature

SNS
PICO Info
in preparation
Languages

English

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