The standardized extract of Centella asiatica L. Urb attenuates the convulsant effect induced by lithium/pilocarpine without affecting biochemical and haematological parameters in rats.

Author: Castañeda-MoralesJuan Manuel, Díaz-VallejoJoel Jahaziel, Rivadeneyra-DomínguezEduardo, Rodríguez-LandaJuan Francisco, Rosales-SánchezÓscar, Zamora-BelloIsaac

Paper Details 
Original Abstract of the Article :
Status epilepticus (SE) is a type of epileptic activity characterized by a failure of the inhibitory mechanisms that limit seizures, which are mainly regulated by the GABAergic system. This imbalance increases glutamatergic neurotransmission and consequently produces epileptic activity. It is also a...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523769/

データ提供:米国国立医学図書館(NLM)

Centella asiatica Extract for Epilepsy Treatment

This study delves into the potential of Centella asiatica, a medicinal plant known for its neuroprotective properties, as a treatment for epilepsy. The researchers investigated the effects of a standardized extract of Centella asiatica on rats subjected to seizures induced by lithium/pilocarpine, a common model for studying epilepsy.

The study revealed that the Centella asiatica extract effectively attenuated the convulsant effect of lithium/pilocarpine without causing any significant adverse effects on biochemical or hematological parameters. This suggests that the extract could be a promising natural alternative for treating epilepsy. Imagine a camel caravan traversing a desert with limited resources - finding a plant that can provide sustenance and healing is crucial for survival. Similarly, Centella asiatica offers a potential natural remedy for a challenging condition like epilepsy.

A Natural Pathway for Epilepsy Treatment

The study highlights the potential of natural remedies for treating epilepsy. It encourages further research to explore the therapeutic potential of Centella asiatica and other natural compounds for this debilitating condition. Just like a camel caravan relies on the resilience of nature for sustenance, we need to explore the vast natural world for potential treatments.

Dr.Camel's Conclusion

This study offers promising evidence for the potential of Centella asiatica as a natural remedy for epilepsy. It underscores the importance of exploring natural compounds for treating complex neurological conditions. Just like a camel caravan relies on the resilience of nature to navigate a harsh desert, we need to tap into the power of the natural world for potential solutions.

Date :
  1. Date Completed 2023-10-04
  2. Date Revised 2023-11-21
Further Info :

Pubmed ID

37759286

DOI: Digital Object Identifier

PMC10523769

Related Literature

SNS
PICO Info
in preparation
Languages

English

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