Paper Details
- Home
- Paper Details
Liver injury in children: signal analysis of suspected drugs based on the food and drug administration adverse event reporting system.
Author: ChengGuo, HuangLiang, JiaZhijun, JiaoXuefeng, LiHailong, LiuYan, WanChaomin, WangHuiqing, ZengLinan, ZhangLei, ZhangLingli, ZhangWei
Original Abstract of the Article :
BACKGROUND: Evidence of drug-induced liver injury is abundant in adults but is lacking in children. Our aim was to identify suspected drug signals associated with pediatric liver injury. METHODS: Hepatic adverse events (HAEs) among children reported in the Food and Drug Administration Adverse Event...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10537493/
データ提供:米国国立医学図書館(NLM)
Identifying Suspected Drug Signals Associated with Pediatric Liver Injury
Drug-induced liver injury is a serious concern, especially in children. Imagine a child playing in a desert, where each drug is a different flower. Some flowers might be harmless, while others could contain toxins. This study delves into the vast database of the Food and Drug Administration Adverse Event Reporting System, like a map of the desert, to identify suspected drug signals associated with pediatric liver injury. The researchers analyzed reports of hepatic adverse events in children, looking for patterns and trends. They found that certain drugs, like paracetamol, methotrexate, and valproic acid, were more frequently linked to liver injury. The study also identified six new potential drug signals, emphasizing the need for further investigation.
Understanding Drug Safety in Children: New Insights into Pediatric Liver Injury
This study reveals the importance of understanding the potential risks of drugs, especially in children. It's like carefully examining each flower in the desert to ensure it's safe for a child to touch. The findings highlight the need for ongoing monitoring and research to identify drug signals associated with pediatric liver injury, helping to protect children from potential harm.
Dr. Camel's Conclusion
This research emphasizes the importance of vigilance when it comes to drug safety, particularly in children. The study's findings, like precious desert maps, guide us towards safer drug use and emphasize the need for continued research to protect the health of our youngest explorers.
Date :
- Date Completed 2023-10-04
- Date Revised 2023-11-23
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.