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Common antiretroviral combinations are associated with somatic depressive symptoms in women with HIV.

Author: AdimoraAdaora A, DastgheybRaha M, FischlMargaret A, GustafsonDeborah R, JinWei, Konkle-ParkerDeborah, MakiPauline M, MilamJoel, O'halloranJane, OfotokunIgho, Parra-RodriguezLuis, RubinLeah H, SharmaAnjali, SpenceAmanda B, WangYuezhe, WeberKathleen M, XuYanxun

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Specific ART combinations are associated with somatic depressive symptoms in women with HIV (WWH) with chronic depression. Tenofovir alafenamide and cobicistat-boosted elvitegravir and/or darunavir were associated with greater somatic symptoms, while tenofovir disoproxil fumarate and efavirenz or rilpivirine were associated with less somatic depressive symptoms.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: While modern antiretroviral therapy (ART) is highly effective and safe, depressive symptoms have been associated with certain ART drugs. We examined the association between common ART regimens and depressive symptoms in women with HIV (WWH) with a focus on somatic vs. nonsomatic symptoms....See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/37773048

データ提供：米国国立医学図書館（NLM）

Antiretroviral Therapy and Depression: A Complex Landscape in the HIV Desert

The world of HIV treatment is a vast and ever-evolving desert. We strive to find new oases of knowledge to improve the lives of patients living with this chronic disease. This study explores a particular challenge, the association between common antiretroviral therapy (ART) regimens and depressive symptoms in women with HIV.

The study found that specific ART combinations were associated with somatic depressive symptoms in women with chronic depression. This finding suggests that there is a complex interplay between ART and mental health, like a hidden current beneath the surface of the HIV desert. Further research is needed to understand these interactions and optimize treatment regimens for better patient outcomes.

Navigating the Depths of the HIV Desert

This study reveals a hidden challenge in the landscape of HIV treatment. The association between specific ART combinations and somatic depressive symptoms emphasizes the importance of recognizing and addressing mental health needs in women with HIV.

Finding the Oasis of Mental Well-being

This study underscores the need for comprehensive care for women with HIV, addressing both physical and mental health needs. Further research is vital to understand the complex interplay between ART and mental health, helping us to find the oasis of mental well-being for these patients.

Dr.Camel's Conclusion

This study reminds us that the desert of HIV treatment is vast and complex, with hidden challenges like the association between ART and depression. It emphasizes the need for continued research and a holistic approach to care, striving to find the oasis of optimal health for all patients.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-09-29
Further Info :

Pubmed ID

37773048

DOI: Digital Object Identifier

00002030-990000000-00351

Related Literature

Article Analysis
・Effects of cobicistat
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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