Poly(oxyethylene)/Poly(oxypropylene) butyl ether prolongs the repellent effect of N,N-diethyl-3-toluamide on the skin.

Prolonging the Repellent Effect of DEET: A New Oasis in Insect Control

N,N-diethyl-meta-toluamide (DEET) is a widely used insect repellent, but its duration of effectiveness can be limited. This study investigates the potential of incorporating poly(oxyethylene)/poly(oxypropylene) butyl ether (POE-POP) into DEET formulations to enhance its repellent activity. The authors prepared a 10% DEET formulation with and without POE-POP and evaluated its effects on skin retention, permeation, and repellent action against mosquitos.

A Durable Shield: Prolonging DEET's Repellent Action

The study demonstrated that adding POE-POP to DEET formulations prolonged its retention in the superficial layers of the skin, reducing its penetration into deeper tissues. This resulted in a prolonged repellent effect, suggesting that POE-POP could enhance the efficacy and duration of DEET-based insect repellents.

A New Hope for Insect Control: A More Effective and Safer Approach

This research offers a potential strategy for developing more effective and long-lasting insect repellents. The study suggests that combining DEET with POE-POP could enhance its repellent action, providing a more robust and durable protection against insect bites. This could be particularly beneficial for individuals who spend extended time outdoors or who are sensitive to insect bites.

Dr. Camel's Conclusion

This study offers a promising solution for enhancing the repellent action of DEET. The addition of POE-POP to DEET formulations prolongs its retention in the skin, resulting in a more durable and effective protection against insect bites. This could be particularly beneficial for those who spend extended time outdoors or who are sensitive to insect bites.