Linezolid-Induced Pancreatitis Associated with Lactic Acidosis and Relative Hypoglycemia: A Rare Case Report.

Author: AdamEhab, AliAteeque Mohamed, AnsariSoubiya Mohammed Rizwan, EltahirMugahid, KimGi Eun

Paper Details 
Original Abstract of the Article :
BACKGROUND: Linezolid is known to cause side effects, including nausea, diarrhea, and headaches of short duration. As extended use of linezolid is becoming more common, additional rare side effects should be considered. CASE PRESENTATION: A 68-year-old man hospitalized for osteomyelitis developed s...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545144/

データ提供:米国国立医学図書館(NLM)

Linezolid-Induced Pancreatitis: A Rare Case of Unforeseen Side Effects

This case report describes a rare instance of linezolid-induced pancreatitis in a 68-year-old man receiving extended treatment for osteomyelitis. The patient developed severe abdominal pain, altered mental status, and laboratory findings consistent with pancreatitis. The authors highlight the importance of considering drug-induced pancreatitis as a potential side effect of linezolid, especially in patients receiving prolonged treatment. The case report also emphasizes the importance of monitoring patients for a triad of adverse effects, including pancreatitis, hypoglycemia, and lactic acidosis, which can be associated with extended linezolid use.

A Mirage in the Desert of Linezolid Side Effects

The desert of drug side effects can be deceptive, with rare and unexpected events occasionally emerging. This case report serves as a reminder that even commonly used medications can have unforeseen consequences, especially when used for prolonged periods. The authors’ findings emphasize the importance of vigilance in monitoring patients for potential adverse reactions, especially when using medications with known side effect profiles.

Navigating the Complexities of Drug Safety

The desert of drug safety is vast and complex, requiring a constant vigilance to ensure the well-being of patients. This case report, like a skilled navigator encountering an unexpected storm, highlights the importance of ongoing research and monitoring to identify and manage potential drug-induced complications. The authors’ findings underscore the importance of considering rare but serious side effects, even with medications considered generally safe.

Dr.Camel's Conclusion

This case report, like a lone traveler encountering an unexpected obstacle in the desert, underscores the importance of vigilance in monitoring patients for potential drug-induced complications. The findings highlight the potential for rare but serious side effects, even with medications considered generally safe. The study serves as a reminder of the importance of ongoing research and careful monitoring to ensure drug safety and optimize treatment outcomes.
Date :
  1. Date Completed n.d.
  2. Date Revised 2023-10-05
Further Info :

Pubmed ID

37789976

DOI: Digital Object Identifier

PMC10545144

Related Literature

SNS
PICO Info
in preparation
Languages

English

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