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Characteristics of adverse drug reactions induced by flutamide and bicalutamide: a real-world pharmacovigilance study using FAERS.

Author: SunYu, XuHongbin, XuTao, ZhuSuyan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

A review of the US Food and Drug Administration Adverse Event Reporting System (FAERS) identified 29 signals for flutamide and 84 for bicalutamide. Liver function test was the most common adverse event for flutamide, and malignant neoplasm progression was the most common for bicalutamide.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Flutamide and bicalutamide are indicated for the management of prostate metastatic carcinoma. The current study evaluated the adverse drug reactions related to flutamide and bicalutamide in a real-world setting. METHODS: To quantify the signals of flutamide and bicalutamide associated a...See full text at original site
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引用元：
https://doi.org/10.1080/14740338.2023.2267978

データ提供：米国国立医学図書館（NLM）

Adverse Drug Reactions of Flutamide and Bicalutamide: A Pharmacovigilance Study

Flutamide and bicalutamide, medications used in the treatment of prostate cancer, are like two different types of desert plants, each with its unique properties and potential side effects. This pharmacovigilance study, a meticulous exploration of real-world data, investigates the adverse drug reactions associated with these medications.

Mapping the Landscape of Adverse Reactions: Understanding Flutamide and Bicalutamide

This study, akin to mapping a vast desert landscape, identified 29 signals for flutamide and 84 signals for bicalutamide, uncovering potential side effects not previously recognized. This research is a valuable resource for healthcare professionals and patients alike, providing a more comprehensive understanding of these medications and their potential risks.

Navigating the Desert of Medication: Awareness and Informed Decision-Making

This study underscores the importance of awareness regarding potential adverse drug reactions. It encourages open communication between patients and healthcare providers to ensure informed decision-making, especially when considering medications with complex side effect profiles. This research is a reminder that even the most helpful treatments can have unintended consequences and requires careful monitoring and management.

Dr. Camel's Conclusion

This study, like a guidebook through a desert of medications, highlights the importance of vigilance and informed decision-making when it comes to managing health conditions. This research underscores the critical role of pharmacovigilance in identifying potential risks and ensuring the safety of medications.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-10-16
Further Info :

Pubmed ID

37795911

DOI: Digital Object Identifier

10.1080/14740338.2023.2267978

Related Literature

Article Analysis
・Side Effects of bicalutamide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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