Paper Details 
Original Abstract of the Article :
Enzyme therapy for celiac disease (CeD), which digests gliadin into non-immunogenic and non-toxic peptides, can be an appropriate treatment option for CeD. Here, we have investigated the effectiveness of bromelain and ficin on gliadin digestion using in vitro, such as SDS-PAGE, HPLC, and circular di...See full text at original site
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引用元:
https://doi.org/10.1007/s00726-023-03333-x

データ提供:米国国立医学図書館(NLM)

Bromelain and Ficin: Potential Enzyme Therapy for Celiac Disease

This study explores the potential of [bromelain and ficin], [proteolytic enzymes], as a treatment option for [celiac disease (CeD)]. The researchers investigated the effects of these enzymes on the [digestion of gliadin], a [protein] found in [wheat] that triggers [immune responses] in individuals with [CeD]. They discovered that [bromelain and ficin] effectively [digested gliadin] into [non-immunogenic and non-toxic peptides], reducing its [cytotoxicity] in [Caco-2 cells]. The study highlights the potential of [enzyme therapy] as a promising approach for managing [CeD] symptoms.

Digesting the Challenges of Celiac Disease

This research provides a compelling case for exploring [enzyme therapy] as a treatment option for [CeD]. The study's findings suggest that [bromelain and ficin] can effectively [digest gliadin] into [non-toxic peptides], mitigating its harmful effects on [intestinal cells]. This study, like a desert oasis providing relief from the scorching sun, offers a refreshing perspective on managing [CeD] symptoms.

Hope for Celiac Disease Sufferers

This research offers a ray of hope for individuals with [CeD] by exploring the potential of [enzyme therapy] to manage the debilitating symptoms of this disorder. The study's findings underscore the importance of continued research into alternative treatments for [CeD] to improve the quality of life for those affected. Like a desert traveler seeking solace in a hidden oasis, this research provides a glimmer of hope for those struggling with [CeD] and opens the door to new possibilities for managing this challenging condition.

Dr.Camel's Conclusion

This study explores the potential of [bromelain and ficin] as an [enzyme therapy] for [Celiac disease]. The research highlights the importance of exploring alternative treatment options for managing this challenging condition and underscores the need for continued research in this area. This study, like a desert wind carrying a message of hope, reminds us that even in the midst of challenges, there is always the potential for new discoveries and breakthroughs.

Date :
  1. Date Completed 2023-12-04
  2. Date Revised 2023-12-04
Further Info :

Pubmed ID

37803248

DOI: Digital Object Identifier

10.1007/s00726-023-03333-x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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