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[Recurrent tinea corporis generalisata due to Terbinafine-resistant Trichophyton rubrum strain : Long-term treatment with super bioavailability itraconazole].

Author: BurmesterAnke, EbertAndreas, MonodMichel, NenoffPietro, SchallerMartin, StahlMaren, UhrlaßSilke

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This case report describes the treatment of a patient with recurrent and therapy-refractory dermatophytosis caused by Trichophyton rubrum. The patient developed terbinafine resistance, confirmed by in vitro testing and sequencing of the squalene epoxidase gene. Itraconazole, in the form of SUBA itraconazole, was ultimately successful in suppressing the dermatophytosis.
Paper Details　
Original Abstract of the Article :
For more than 30 years, an 82-year-old man has been suffering from tinea corporis generalisata in the sense of Trichophyton rubrum syndrome. The patient received long-term treatment with terbinafine. Fluconazole had no effect. There was an increase in liver enzymes with itraconazole. Super bioa...See full text at original site
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引用元：
https://doi.org/10.1007/s00105-023-05232-4

データ提供：米国国立医学図書館（NLM）

Recurrent Tinea Corporis Generalisata: A Case of Terbinafine Resistance

This case report takes us into the world of dermatology, where we encounter a patient with a persistent skin infection. The patient had a long history of tinea corporis generalisata, caused by a terbinafine-resistant strain of Trichophyton rubrum, like a persistent desert bloom that refuses to die. The authors describe the challenges of managing this resistant infection, which required a long-term treatment with itraconazole. The case highlights the importance of considering drug resistance in dermatophytosis and using appropriate diagnostic and treatment strategies. It's like encountering a particularly resilient desert plant that requires specialized knowledge and treatment to control.

The Challenges of Drug Resistance

The case report underscores the challenges of drug resistance in dermatophytosis, a common skin infection. The patient's case exemplifies the importance of considering drug resistance when treating these infections. It's like encountering a particularly thorny desert plant that requires a different approach to manage. The study highlights the need for careful monitoring and appropriate treatment strategies to prevent the development of resistance.

Managing Resistant Infections

The case highlights the importance of using appropriate diagnostic and treatment strategies for resistant dermatophytosis. The authors emphasize the need for careful monitoring and potential alternative treatments. It's like learning to navigate a new desert, understanding the specific challenges and finding the right tools to overcome them. This case study offers valuable insights into managing these resistant infections.

Dr.Camel's Conclusion

This case report is a reminder that the desert of dermatophytosis can be full of hidden dangers, like a cactus with sharp spines. The case highlights the challenges of drug resistance and emphasizes the importance of personalized treatment strategies to ensure the best possible outcomes for patients.

Date :
  1. Date Completed 2023-11-01
  2. Date Revised 2023-11-01
Further Info :

Pubmed ID

37823916

DOI: Digital Object Identifier

10.1007/s00105-023-05232-4

SNS
PICO Info
in preparation
Languages

German

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