Paper Details

  1. Home
  2. Paper Details

Exosomal microRNA profiling revealed enhanced autophagy suppression and anti-tumor effects of a combination of compound Phyllanthus urinaria and lenvatinib in hepatocellular carcinoma.

Author: ChenNing, DuHaiyan, HuangDanping, HuangHoushuang, LiaoMianmian, LiuLinhua, QinMeirong, TongGuangdong, WangPing, ZhouHua

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Compound Phyllanthus urinaria (CP) is a traditional Chinese herbal remedy with anti-cancer effects. This review discusses the potential benefits of co-administering CP with lenvatinib, an oral tyrosine kinase inhibitor, for treating hepatocellular carcinoma (HCC).
Paper Details　
Original Abstract of the Article :
Compound Phyllanthus urinaria (CP), a traditional Chinese herbal remedy, possesses strong anti-cancer effects and is extensively employed in the clinical management of hepatocellular carcinoma (HCC). While lenvatinib and other oral tyrosine kinase inhibitors have been authorized as initial treatment...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.phymed.2023.155091

データ提供：米国国立医学図書館（NLM）

Compound Phyllanthus Urinaria and Lenvatinib: A Powerful Duo Against Hepatocellular Carcinoma

The fight against hepatocellular carcinoma (HCC) is a challenging battle, akin to a relentless sandstorm in the desert. This study, like a strategic expedition, explores the synergistic potential of combining Compound Phyllanthus Urinaria (CP), a traditional Chinese herbal remedy, with lenvatinib, an oral tyrosine kinase inhibitor, in the treatment of HCC.

CP and Lenvatinib: A Promising Oasis in the HCC Desert

The researchers found that the combination of CP and lenvatinib significantly enhanced the anti-tumor effects, leading to improved autophagy suppression and enhanced therapeutic efficacy. This powerful duo, like a well-equipped caravan navigating the treacherous desert landscape, offers a promising approach to combating HCC.

Navigating the HCC Desert

This research provides valuable insights into the potential of combining traditional remedies with modern therapies in the fight against HCC. The synergistic effect of CP and lenvatinib offers a beacon of hope in the desert of this challenging disease, potentially paving the way for more effective and personalized treatments.

Dr.Camel's Conclusion

This study highlights the potential of combining traditional Chinese herbal remedies with modern therapies in the fight against HCC. The synergistic effects of CP and lenvatinib offer a promising oasis in the desert of this challenging disease, suggesting a potential for more effective and personalized treatment approaches.

Date :
  1. Date Completed 2023-11-14
  2. Date Revised 2023-11-14
Further Info :

Pubmed ID

37844378

DOI: Digital Object Identifier

10.1016/j.phymed.2023.155091

Related Literature

Article Analysis
・Effects of lenvatinib
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.