Idarucizumab for Emergency Reversal of the Anticoagulant Effects of Dabigatran: Final Results of a Japanese Postmarketing Surveillance Study.

Author: AsakuraHidesaku, KimotoTakaaki, NakayamaDaisuke, OgiYukako, SuzukiMichiyasu, YamaneTeiichi, YasakaMasahiro, YokotaHiroyuki

Paper Details 
Original Abstract of the Article :
Idarucizumab, a monoclonal antibody fragment that rapidly reverses the anticoagulant effects of dabigatran, was approved in Japan in September 2016, at which time an all-case, postmarketing surveillance (PMS) study was initiated to collect data on idarucizumab in Japanese patients. Interim results w...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10704007/

データ提供:米国国立医学図書館(NLM)

Idarucizumab: A Rapid Reversal Agent for Dabigatran Anticoagulation

This research reports the final results of a postmarketing surveillance study on idarucizumab, a monoclonal antibody fragment that rapidly reverses the anticoagulant effects of dabigatran, a drug used to prevent blood clots. The study, conducted in Japan, collected data on the use of idarucizumab in patients experiencing complications related to dabigatran anticoagulation. The researchers analyzed the safety and efficacy of idarucizumab in this real-world setting, providing valuable insights into its clinical use.

Idarucizumab: A Timely Intervention for Dabigatran-Related Complications

This study confirms the effectiveness of idarucizumab in rapidly reversing the anticoagulant effects of dabigatran. The researchers found that idarucizumab was safe and effective in a real-world setting, providing a timely and reliable intervention for patients experiencing bleeding or other complications related to dabigatran therapy. This finding is particularly important given the potential risks associated with uncontrolled bleeding, emphasizing the importance of having a safe and effective reversal agent available.

Considerations for Dabigatran Use and Idarucizumab Reversal

This research highlights the importance of having a safe and effective reversal agent available for patients receiving dabigatran therapy. While dabigatran is a valuable medication for preventing blood clots, it is essential to be prepared for potential complications. This research provides valuable information for healthcare providers on the use of idarucizumab in managing dabigatran-related complications.

Dr.Camel's Conclusion

This research provides valuable insights into the real-world use of idarucizumab as a reversal agent for dabigatran anticoagulation. The study's findings underscore the importance of having a safe and effective reversal agent available for patients receiving anticoagulation therapy, offering peace of mind for both patients and healthcare providers.
Date :
  1. Date Completed n.d.
  2. Date Revised 2023-12-10
Further Info :

Pubmed ID

37845427

DOI: Digital Object Identifier

PMC10704007

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English

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