Effects of protriptyline on sleep related disturbances of breathing in restrictive chest wall disease.

Author: BranthwaiteM A, ParkerR A, SimondsA K

Paper Details 
Original Abstract of the Article :
The effects of protriptyline on sleep stage distribution and gas exchange have been assessed in eight patients with nocturnal hypoventilation secondary to restrictive chest wall disease. At a dose of 10-20 mg taken when they retired the total sleeping time was unaltered but the proportion of rapid e...See full text at original site
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引用元:
https://doi.org/10.1136/thx.41.8.586

データ提供:米国国立医学図書館(NLM)

Protriptyline: A Potential Solution in the Desert of Restrictive Chest Wall Disease

Restrictive chest wall disease, a condition that limits lung expansion, is like a desert storm, constricting the flow of life-giving air. This study, like a group of researchers seeking a breath of fresh air for patients, investigates the effects of protriptyline, a tricyclic antidepressant, on sleep-related breathing disturbances in individuals with this condition. The researchers focused on the impact of protriptyline on sleep stage distribution and gas exchange, aiming to improve sleep quality and reduce the risk of oxygen deprivation.

Protriptyline: A Potential Oasis in the Desert of Breathing Disorders

The study's findings, like a refreshing breeze in the desert, reveal that protriptyline shows promise in improving sleep quality and reducing sleep-related breathing disturbances in patients with restrictive chest wall disease. By reducing REM sleep, protriptyline effectively minimizes the severity of nocturnal hypoventilation, a condition characterized by reduced oxygen levels during sleep, like a caravan finding shelter from a desert storm.

A New Pathway in the Desert of Respiratory Health: A Focus on Sleep

This research, like a well-traveled path through the desert, highlights the importance of addressing sleep-related breathing disturbances in patients with restrictive chest wall disease. The findings suggest that protriptyline, while traditionally used for mood disorders, may offer a potential therapeutic option for improving sleep quality and reducing the risk of oxygen deprivation. This approach, like a desert oasis offering respite from the heat, can significantly enhance quality of life for patients.

Dr. Camel's Conclusion

This study, like a beacon of hope in the desert, reveals the potential of protriptyline to alleviate sleep-related breathing disturbances in patients with restrictive chest wall disease. The findings offer a new pathway for improving sleep quality and potentially enhancing overall well-being for those living with this challenging condition.

Date :
  1. Date Completed 1987-01-21
  2. Date Revised 2019-05-03
Further Info :

Pubmed ID

3787541

DOI: Digital Object Identifier

10.1136/thx.41.8.586

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SNS
PICO Info
in preparation
Languages

English

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