Effects of gabapentin on intraocular pressure, tear production and horizontal pupil diameter in New Zealand White rabbits.

Author: CinarHarun, DanismanIbrahim T, IsilAyhan, YanmazLatif E

Paper Details 
Original Abstract of the Article :
BACKGROUND: This study aimed to investigate the effects of gabapentin on various ocular parameters in New Zealand White rabbits. METHODS: A randomised, placebo-controlled crossover study design was employed. Eight New Zealand White rabbits were randomly assigned to receive either oral gabapentin at...See full text at original site
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引用元:
https://doi.org/10.1002/vetr.3558

データ提供:米国国立医学図書館(NLM)

The Ocular Effects of Gabapentin: A Detailed Examination

This randomized, placebo-controlled crossover study delves into the realm of [pharmacology] and [ocular effects]. The research investigates the effects of [gabapentin] on various [ocular parameters] in [New Zealand White rabbits], including [intraocular pressure], [tear production], and [horizontal pupil diameter]. The study found that [gabapentin] did not significantly affect any of the [ocular parameters] measured, suggesting that it may not have a major impact on the eye in healthy rabbits. However, the study observed some [muscle relaxation] and [behavioral changes] in the rabbits treated with [gabapentin], highlighting the need for further research into its potential side effects.

Gabapentin: A Closer Look at its Ocular Effects

This study sheds light on the potential [ocular effects] of [gabapentin] in a healthy model. The findings suggest that [gabapentin] may not have a significant impact on [intraocular pressure], [tear production], or [pupil diameter] in [rabbits]. However, the study observed some [muscle relaxation] and [behavioral changes], indicating that further research is necessary to fully understand the potential side effects of [gabapentin] on the eyes.

Navigating the Ocular Landscape: Understanding Gabapentin

This research offers valuable insights into the potential [ocular effects] of [gabapentin], a commonly used medication. While the study suggests that [gabapentin] may not have a major impact on [intraocular pressure], [tear production], or [pupil diameter] in healthy rabbits, it also highlights the importance of considering potential side effects. It's like navigating a desert landscape where subtle shifts in the terrain can impact your journey. It's crucial to be aware of potential side effects and adjust our course accordingly.

Dr.Camel's Conclusion

Just like a camel traversing the vast and varied desert landscape, we must be mindful of the potential impact of medications on our bodies, even those that seem benign. This research provides valuable insights into the [ocular effects] of [gabapentin], suggesting that further exploration is needed to fully understand its potential effects on the eye. It's like carefully examining the shifting sands of the desert to ensure a smooth and safe journey.
Date :
  1. Date Completed 2023-12-04
  2. Date Revised 2023-12-04
Further Info :

Pubmed ID

37886849

DOI: Digital Object Identifier

10.1002/vetr.3558

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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