Paper Details 
Original Abstract of the Article :
The development of efficient tools for predicting drug-induced cardiotoxicity in the preclinical phase would greatly benefit the drug development process. This study presents an SU-8 cantilever integrated with a single-crystal silicon strain sensor to enhance force sensitivity in toxicity screening ...See full text at original site
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引用元:
https://doi.org/10.1016/j.bios.2023.115756

データ提供:米国国立医学図書館(NLM)

A New Tool for the Desert of Drug Testing: Enhancing Cardiomyocyte Contraction Force Measurement

Imagine a tiny oasis, a single cardiomyocyte, pulsating rhythmically, reflecting the heart's strength and vitality. This study introduces a novel tool for measuring the force of contraction in these vital cells, an essential step in drug testing. The researchers developed a highly sensitive strain sensor integrated into a cantilever, allowing for precise and accurate measurements of cardiomyocyte contraction force, providing a better understanding of potential drug-induced cardiotoxicity.

A More Precise Oasis: Enhancing Cardiomyocyte Contraction Force Measurement

This innovative tool, like a powerful magnifying glass in the desert, provides a more precise and sensitive way to measure the contraction force of cardiomyocytes, offering crucial insights into potential drug-induced effects on the heart. This advancement holds promise for improving drug safety assessments and protecting heart health.

Navigating the Desert of Drug Development: Staying Safe and Informed

It is essential to be aware of potential drug-induced cardiotoxicity. Consulting a healthcare professional to discuss any concerns or potential side effects is crucial for ensuring your safety.

Dr.Camel's Conclusion

This study offers a powerful new tool for navigating the desert of drug testing. By enhancing the precision and sensitivity of cardiomyocyte contraction force measurements, this innovation provides a vital step toward ensuring drug safety and protecting the heart's delicate oasis in the human body.

Date :
  1. Date Completed 2023-11-06
  2. Date Revised 2023-11-06
Further Info :

Pubmed ID

37898097

DOI: Digital Object Identifier

10.1016/j.bios.2023.115756

Related Literature

SNS
PICO Info
in preparation
Languages

English

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