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The Pharmacokinetics, Safety, and Tolerability of Rimegepant 75 mg Are Similar in Elderly and Nonelderly Adults: A Phase 1, Open-Label, Parallel-Group, Single-Dose Study.
Author: BertzRichard, BhardwajRajinder, CroopRobert, LiuJing, MorrisBeth
Original Abstract of the Article :
Rimegepant is a small-molecule calcitonin gene-related peptide receptor antagonist approved for the acute treatment of migraine ± aura and preventive treatment of migraine in adults. The pharmacokinetics of rimegepant in elderly and nonelderly subjects were evaluated. In an open-label Phase 1 study,...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1002/cpdd.1337
データ提供:米国国立医学図書館(NLM)
Rimegepant for Migraine: Pharmacokinetics in Elderly Adults
Migraine, a debilitating headache disorder, can be like a persistent desert mirage, taunting those who seek relief. This research investigates the pharmacokinetics of rimegepant, a medication for the acute treatment of migraine, in elderly adults. The study aims to determine whether dose adjustments are needed for older patients. It's like exploring the impact of age on the body's ability to absorb and process medications, ensuring that the treatment remains effective and safe for all individuals, regardless of their age.
Rimegepant: Navigating the Migraine Desert
The study found that rimegepant's pharmacokinetic profile was similar in elderly and nonelderly adults, suggesting that dose adjustments are not necessary. It's like finding a universal water source in the desert, accessible and beneficial to all travelers, regardless of their age or background.
A Safe and Effective Treatment for All
This research offers reassurance for older adults suffering from migraine, indicating that rimegepant can provide effective relief without the need for dose adjustments. It's like discovering a welcoming oasis, open to all who seek refuge from the scorching desert sun.
Dr.Camel's Conclusion
This study provides valuable insights into the use of rimegepant for migraine in elderly adults. It's like discovering a new and reliable path through the desert of migraine, offering hope for those who have long struggled to find relief. The study emphasizes the importance of tailoring treatment strategies to individual needs and ensuring that medications are safe and effective for people of all ages.
Date :
- Date Completed n.d.
- Date Revised 2023-10-31
Further Info :
Related Literature
English
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