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Effects of Chemotherapy on the Immune System: Implications for Cancer Treatment and Patient Outcomes.

Author: JasrotiaShivam, KumarAjay, SharmaAnirudh

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review discusses the impact of chemotherapy on the immune system, highlighting its ability to induce immune suppression, which can weaken the anti-tumor immune response and increase the risk of immune-related toxicities. Strategies for mitigating immune suppression, including immunomodulatory agents, combination therapies, and supportive care measures, are discussed, emphasizing the need for personalized cancer treatment approaches.
Paper Details　
Original Abstract of the Article :
Chemotherapy is a cornerstone of cancer treatment, but it can also induce immune suppression, which can have significant implications for patient outcomes. This review paper aims to give a general overview of how chemotherapy affects the immune system and how it affects cancer treatment. Chemotherap...See full text at original site
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引用元：
https://doi.org/10.1007/s00210-023-02781-2

データ提供：米国国立医学図書館（NLM）

Chemotherapy and the Immune System: A Balancing Act in the Desert of Cancer

Chemotherapy, while a powerful tool in the fight against cancer, can have a significant impact on the immune system. This review explores the complex interplay between chemotherapy and the immune system, highlighting the potential consequences of immune suppression for cancer treatment outcomes. The authors delve into the mechanisms of chemotherapy-induced immune suppression and discuss strategies for mitigating its effects.

Navigating the Shifting Sands of Immunity

The review reveals how chemotherapy can directly impact immune cells, leading to a range of effects, including cytotoxicity, altered cell differentiation and function, and disruption of cell communication pathways. This immune suppression can weaken the body's ability to fight cancer and increase the risk of infections. The authors explore strategies for minimizing these effects, including the use of immunomodulatory agents, combination therapies, and supportive care measures.

A Delicate Balance in the Desert of Cancer

This review underscores the importance of understanding and managing chemotherapy-induced immune suppression to optimize cancer treatment outcomes. It's like navigating a desert landscape where the path to recovery requires a delicate balance between fighting cancer and maintaining a strong immune system.

Dr. Camel's Conclusion

This review offers a valuable roadmap for navigating the complex terrain of chemotherapy and the immune system. It highlights the importance of carefully considering the potential impact of chemotherapy on immune function and employing strategies to minimize immune suppression while maximizing the effectiveness of cancer treatment.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-10-31
Further Info :

Pubmed ID

37906273

DOI: Digital Object Identifier

10.1007/s00210-023-02781-2

Related Literature

Article Analysis
・Effective treatment of immune system
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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