Paper Details 
Original Abstract of the Article :
Theophylline has been used for decades as a bronchodilator to treat asthma and chronic obstructive pulmonary disease (COPD). The precise mode of action is still uncertain. Since beta-2 agonists are at least as effective as theophylline as a bronchodilator while having fewer side effects, theophyllin...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631770/

データ提供:米国国立医学図書館(NLM)

Theophylline Toxicity: A Hidden Danger in Long-Term Users

This case report, like a camel navigating a treacherous desert landscape, highlights the potential for theophylline toxicity in patients on long-term theophylline therapy, even when they present with nonspecific symptoms. The patient, a COPD sufferer, had been taking theophylline for an extended period without regular level monitoring. He presented with vague gastrointestinal symptoms and was initially suspected of having gastrointestinal cancer due to weight loss caused by decreased oral intake. However, due to his long-term theophylline use and lack of regular monitoring, theophylline toxicity was suspected and confirmed. The case report serves as a reminder that theophylline toxicity can be a serious concern in patients on long-term therapy, especially when patients are not consistently monitored.

The Importance of Monitoring Theophylline Levels

The case report underscores the importance of regular theophylline level monitoring in patients on long-term therapy. The patient's case demonstrates the dangers of neglecting this essential step in patient care. This case highlights the importance of monitoring theophylline levels in patients on long-term therapy. While theophylline can be an effective treatment for asthma and COPD, its narrow therapeutic window and the potential for severe side effects, including fatal convulsions, require vigilance.

Recognizing Theophylline Toxicity: A Clinical Challenge

The case report highlights the diagnostic challenges posed by theophylline toxicity. The nonspecific gastrointestinal symptoms experienced by the patient can easily lead to misdiagnosis. Clinicians should be aware of the potential for theophylline toxicity in patients on long-term therapy and maintain a high index of suspicion, especially when patients present with nonspecific symptoms.

Dr.Camel's Conclusion

This case report, like a camel navigating a treacherous desert landscape, serves as a stark reminder of the potential for theophylline toxicity, even in patients on long-term therapy. The nonspecific symptoms and the potential for severe consequences highlight the importance of regular monitoring of theophylline levels and maintaining a high index of suspicion for theophylline toxicity in patients on long-term therapy. The camel of medicine continues to search for the perfect oasis of treatment, one that offers both efficacy and safety for patients with respiratory conditions, while remaining vigilant for potential drug-related complications.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-11-11
Further Info :

Pubmed ID

37946855

DOI: Digital Object Identifier

PMC10631770

Related Literature

SNS
PICO Info
in preparation
Languages

English

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