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Silica nanoparticles containing nano-silver and chlorhexidine respond to pH to suppress biofilm acids and modulate biofilms toward a non-cariogenic composition.
Author: ChengLei, FangLixin, LiuFei, MasriRadi, OatesThomas W, WangMan, WangSuping, WangYiyi, WeirMichael D, XuHockin H K, ZhengHao, ZhouHuoxiang
Original Abstract of the Article :
Dental caries is caused by acids from biofilms. pH-sensitive nanoparticle carriers could achieve improved targeted effectiveness. The objectives of this study were to develop novel mesoporous silica nanoparticles carrying nanosilver and chlorhexidine (nMS-nAg-Chx), and investigate the inhibition of ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.dental.2023.11.006
データ提供:米国国立医学図書館(NLM)
Fighting Caries: A Novel Approach with pH-Sensitive Nanoparticles
Dental caries, a prevalent oral health problem, is like a relentless sandstorm eroding the enamel of our teeth. This study, like a desert explorer seeking a sustainable solution to combat desertification, investigates the potential of a novel silica nanoparticle delivery system to fight caries, a significant dental concern. This research, like a wise desert guide navigating the intricate landscape of oral health, introduces a new strategy for fighting caries, offering a potentially more effective and targeted approach to combatting this prevalent condition.
Researchers, using a combination of nanotechnology and biomaterials, developed pH-sensitive silica nanoparticles loaded with nanosilver and chlorhexidine (nMS-nAg-Chx). These nanoparticles effectively suppress biofilm acids, the primary cause of caries, and modulate the biofilm composition towards a non-cariogenic state. This research, like a skilled desert farmer cultivating a flourishing oasis, demonstrates a promising approach to control biofilm acidity and potentially prevent caries.
nMS-nAg-Chx Nanoparticles: A Powerful Weapon Against Caries
This study highlights the potential of nMS-nAg-Chx nanoparticles to combat caries, a common dental concern. These nanoparticles, like a desert explorer discovering a new source of water, offer a promising solution for managing biofilm acidity and promoting a healthier oral environment.
The Future of Caries Prevention: A Journey Toward Brighter Smiles
This research underscores the importance of developing innovative strategies to combat dental caries. By exploring the potential of nMS-nAg-Chx nanoparticles, researchers are paving the way for more effective and targeted approaches to prevent caries, offering a brighter future for healthier smiles.
Dr.Camel's Conclusion
This study offers a compelling solution for combating dental caries, a prevalent oral health problem. nMS-nAg-Chx nanoparticles, like a desert oasis offering respite from the harsh elements, demonstrate a promising strategy for controlling biofilm acidity and promoting a healthier oral environment. This research represents a significant step in the ongoing journey to combat caries and ensure healthier smiles for everyone.
Date :
- Date Completed n.d.
- Date Revised 2023-11-11
Further Info :
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English
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