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Retinoid X Receptor agonists as selective modulators of the immune system for the treatment of cancer.

Author: ChowdhuryAfrin Sultana, HungPei-Yu, LealAna S, LibyKaren T

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review explores the role of retinoid X receptors (RXR) in regulating inflammation and tumor immunity. The study discusses how RXR agonists can modulate the tumor microenvironment by influencing both inflammation and immune responses. The review highlights the potential of RXR-dependent immune cell modulation as a therapeutic strategy for cancer treatment and prevention.
Paper Details　
Original Abstract of the Article :
Upon heterodimerizing with other nuclear receptors, retinoid X receptors (RXR) act as ligand-dependent transcription factors, regulating transcription of critical signaling pathways that impact numerous hallmarks of cancer. By controlling both inflammation and immune responses, ligands that activate...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://pubmed.ncbi.nlm.nih.gov/37952906

データ提供：米国国立医学図書館（NLM）

Retinoid X Receptor Agonists: A New Frontier in Cancer Treatment

The vast desert of cancer research is constantly evolving, with researchers seeking new and innovative treatments. This study explores the potential of retinoid X receptor (RXR) agonists as a novel approach to cancer therapy, focusing on their ability to modulate the immune system and influence the tumor microenvironment.

RXR Agonists: A New Weapon in the Fight Against Cancer

The authors highlight the multifaceted role of RXR signaling in regulating inflammation and immune responses. By activating RXR, these agonists can modulate the tumor microenvironment, potentially enhancing anti-tumor immune responses and inhibiting tumor growth. This research provides a compelling case for further investigation into the therapeutic potential of RXR agonists in cancer treatment.

The Promise of RXR Agonists in Cancer Therapy

This study offers a ray of hope in the desert of cancer research. RXR agonists hold the potential to revolutionize cancer treatment, harnessing the power of the immune system to combat disease. Further research and clinical trials are needed to fully explore the efficacy and safety of these promising agents.

Dr.Camel's Conclusion

This research is like a refreshing spring oasis in the desert of cancer research. It offers a novel approach to cancer treatment, utilizing the body's own immune system to fight disease.

Date :
  1. Date Completed 2023-12-04
  2. Date Revised 2023-12-09
Further Info :

Pubmed ID

37952906

DOI: Digital Object Identifier

NIHMS1945873

Related Literature

Article Analysis
・Effective treatment of immune system
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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