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Effect of Regular Consumption of a Miraculin-Based Food Supplement on Taste Perception and Nutritional Status in Malnourished Cancer Patients: A Triple-Blind, Randomized, Placebo-Controlled Clinical Trial-CLINMIR Pilot Protocol.
Author: Bensadon-NaederLoan, Feliú-BatlleJaime, GilÁngel, HummelThomas, López-PlazaBricia, Menéndez-ReyAdrián, Palma-MillaSamara
Original Abstract of the Article :
Taste disorders are common among cancer patients undergoing chemotherapy, with a prevalence ranging from 20% to 86%, persisting throughout treatment. This condition leads to reduced food consumption, increasing the risk of malnutrition. Malnutrition is associated not only with worse treatment effica...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648678/
データ提供:米国国立医学図書館(NLM)
Improving Taste Perception in Malnourished Cancer Patients
The world of cancer treatment is vast and complex, with a plethora of challenges for patients. One such challenge is taste disorders, which can be a significant barrier to adequate nutrition. This is especially true for malnourished cancer patients undergoing chemotherapy. These patients are at higher risk of experiencing taste distortions, leading to a reduced appetite and subsequent nutritional deficiencies. The consequences of malnutrition can be severe, impacting treatment efficacy, disease prognosis, and overall quality of life. The CLINMIR Pilot Protocol is a groundbreaking study focusing on the potential of miraculin, a taste-modifying protein found in the miracle berry, to improve taste perception and nutritional status in malnourished cancer patients.
Miraculin: A Potential Game-Changer for Cancer Patients
The study is designed as a triple-blind, randomized, placebo-controlled clinical trial, with 30 patients divided into three groups, each receiving a different dose of miraculin-based food supplement or a placebo. Researchers will meticulously assess various parameters related to taste perception, nutritional status, and overall health over a period of three months. This includes measuring electrical and chemical taste perception, smell perception, nutritional assessment, dietary habits, quality of life, and even analyzing the fatty acid profile of erythrocytes, inflammatory and cancer-associated cytokines, oxidative stress, and the gut microbiota.
A Ray of Hope for Malnourished Cancer Patients
The primary anticipated result is a significant improvement in food taste perception among malnourished cancer patients with taste distortion. This improvement could translate into increased food intake, ultimately leading to an improvement in their nutritional status and mitigating the associated risks. The study also aims to identify the optimal dosage of the miraculin-based food supplement for maximum benefits. The CLINMIR Protocol is a beacon of hope for malnourished cancer patients, offering a potential solution to a major obstacle in their journey towards recovery.
Dr.Camel's Conclusion
It's like finding a hidden oasis in the vast desert of cancer treatment! This study holds the key to unlocking better nutrition for cancer patients struggling with taste disorders. By harnessing the power of miraculin, researchers are seeking to nourish both the body and the spirit, leading to a more positive and sustainable path towards recovery. The journey of cancer treatment can be long and arduous, but the potential for miraculin to alleviate taste distortions and improve nutritional status offers a ray of hope for these patients.
Date :
- Date Completed 2023-11-15
- Date Revised 2023-11-17
Further Info :
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