Quercetin, Main Active Ingredient of Moutan Cortex, Alleviates Chronic Orofacial Pain via Block of Voltage-Gated Sodium Channel.

Author: CaiSong, ChengJing, CheungChi Wai, GuoWeijie, JiangYuanxu, LiuJessica Aijia, LiuZhanli, PanYunping, ShanZhiming, WuChaoran, XingYanmei, YangHaoyi

Paper Details 
Original Abstract of the Article :
Chronic orofacial pain (COP) therapy is challenging, as current medical treatments are extremely lacking. Moutan Cortex (MC) is a traditional Chinese medicine herb widely used for chronic inflammatory diseases. However, the mechanism behind MC in COP therapy has not been well-established. The purpos...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/37968831

データ提供:米国国立医学図書館(NLM)

Unlocking the Potential of Moutan Cortex for Chronic Orofacial Pain

Chronic orofacial pain (COP) is a debilitating condition that affects millions of people worldwide. The field of pain management is constantly seeking new and effective treatment options for COP, aiming to alleviate suffering and improve quality of life. This study delves into the potential of Moutan Cortex (MC), a traditional Chinese medicine herb, as a treatment for COP. The researchers meticulously investigated the active ingredients of MC and their underlying mechanisms of action, focusing on the role of voltage-gated sodium channels. Their findings suggest that quercetin, a key active ingredient in MC, exhibits analgesic properties by blocking voltage-gated sodium channels, offering a promising approach for COP management. This research highlights the importance of exploring traditional medicine and its potential for addressing modern health challenges.

Quercetin: A Potential Breakthrough for Chronic Orofacial Pain

The study's findings suggest that quercetin, a key active ingredient in MC, holds significant promise for COP treatment. The researchers demonstrated that quercetin effectively alleviates COP by blocking voltage-gated sodium channels, a crucial pathway involved in pain transmission. This discovery provides a potential therapeutic target for developing new and effective treatments for COP, offering hope for those suffering from this debilitating condition. This research is a testament to the power of traditional medicine and its potential for addressing modern health challenges.

A Natural Approach to Pain Management: Exploring the Benefits of Moutan Cortex

This study highlights the potential of MC as a natural remedy for COP. The researchers' findings suggest that MC's analgesic properties may stem from quercetin's ability to block voltage-gated sodium channels, a key pathway involved in pain transmission. This discovery opens up new avenues for developing natural-based treatments for COP, offering a potential alternative to synthetic pain relievers. This research is a valuable contribution to the growing field of natural medicine, demonstrating the potential of traditional remedies for addressing modern health challenges.

Dr.Camel's Conclusion

This study is like a camel seeking a hidden oasis in the vast desert of chronic orofacial pain. The researchers meticulously investigate the potential of Moutan Cortex, uncovering the analgesic properties of quercetin. Their findings are a beacon of hope for those suffering from COP, suggesting a natural and potentially effective treatment option. This research underscores the importance of exploring traditional medicine and its potential for addressing modern health challenges.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-11-16
Further Info :

Pubmed ID

37968831

DOI: Digital Object Identifier

00000539-990000000-00659

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SNS
PICO Info
in preparation
Languages

English

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