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Phase 2 LYSA study of prednisone, vinblastine, doxorubicin, bendamustine for untreated older Hodgkin lymphoma patients.
Author: AndreMarc, Berriolo-RiedingerAlina, BonnetChristophe, BurroniBarbara, CasasnovasOlivier, DamotteDiane, FournierMarguerite, GacAnne Claire, GhesquieresHerve, GuidezStéphanie, KanounSalim, KrzischDaphné, LaribiKamel, MorandFabienne, MorschhauserFranck, Nicolas VirelizierEmmanuelle, Orsini PiocelleFrederique, QuittetPhilippe, TouatiMohamed, Traverse-GlehenAlexandra, Waultier RascalouAgathe
Original Abstract of the Article :
Older classical Hodgkin lymphoma (cHL) patients require more effective and less toxic therapies. In this multicenter, prospective, phase 2 study, we investigated a new first-line therapy regimen comprising 6 cycles of prednisone (40 mg/m2 Day 1-5), vinblastine (6 mg/m2, Day 1), doxorubicin (40 mg/m2...See full text at original site
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引用元:
https://doi.org/10.1182/blood.2023021564
データ提供:米国国立医学図書館(NLM)
PVAB Regimen: A Promising Therapy for Older Hodgkin Lymphoma Patients
Hodgkin lymphoma, a type of cancer that affects the lymphatic system, is like a desert sandstorm, sweeping through the body and disrupting its normal functions. This study focuses on older patients with Hodgkin lymphoma, who often face different challenges when it comes to treatment. The researchers investigated a new therapy regimen, called PVAB, which is like a skilled oasis builder, offering a new way to combat this aggressive desert storm. They found that PVAB was effective in achieving a high rate of complete metabolic response (CMR), meaning the cancer was effectively controlled. This is encouraging news, as it suggests that older patients with Hodgkin lymphoma can benefit from a new and potentially less toxic treatment option.
PVAB Regimen: A Powerful Weapon Against Hodgkin Lymphoma
This study reveals the potential of the PVAB regimen as an effective treatment for older patients with Hodgkin lymphoma. The high CMR rate achieved in this study is a significant development, suggesting that PVAB could offer a valuable alternative for older patients who may not tolerate more aggressive therapies. However, it's important to note that while PVAB was well-tolerated, it did have some side effects. The study also emphasizes the importance of long-term follow-up, as some patients experienced relapse or progression of their disease.
Hope for Older Hodgkin Lymphoma Patients
This research offers hope for older patients with Hodgkin lymphoma, suggesting that PVAB could be a valuable treatment option for this challenging disease. The study highlights the need for ongoing research to further optimize treatment strategies for older patients, who often face unique challenges in the fight against cancer.
Dr.Camel's Conclusion
Hodgkin lymphoma, a desert sandstorm sweeping through the body, can be a daunting challenge. This research unveils a new oasis, the PVAB regimen, offering a potentially effective and well-tolerated treatment for older patients. It's a reminder that the fight against cancer is an ongoing journey, and every new discovery brings us closer to finding a safe and effective solution for all patients.
Date :
- Date Completed n.d.
- Date Revised 2023-11-18
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