Pre-treatment inflammatory and immune system parameters predicting cervical cancer metastasis.

Author: AvishaMirah, HamidFirdaus, PelupessyNugraha Utama, RahmanAbdul, RakhmahNur, RaufSyahrul

Paper Details 
Original Abstract of the Article :
OBJECTIVE: This study aimed to evaluate the relationship between mannose-binding lectin-associated serine protease-2 as an immune system parameter and neutrophil lymphocyte ratio (NLR) as an inflammatory parameter to predict cervical cancer metastasis. MATERIALS AND METHODS: This cross-sectional st...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10711526/

データ提供:米国国立医学図書館(NLM)

Predicting Cervical Cancer Metastasis: A Closer Look at Immune and Inflammatory Parameters

The field of oncology is constantly seeking new ways to predict and treat cancer, especially in cases like cervical cancer where metastasis can be life-threatening. This research dives deep into the world of immune and inflammatory markers, investigating their potential as predictors of cervical cancer metastasis. The authors employed a cross-sectional study design, examining a group of cervical cancer patients in Indonesia. Their primary focus was on evaluating the relationship between mannose-binding lectin-associated serine protease-2 (MASP-2) - an immune system parameter - and neutrophil lymphocyte ratio (NLR) - an inflammatory parameter. They delved into the connection between these markers and various aspects of cervical cancer, including stage, metastasis, and lymphovascular invasion. Their findings revealed a strong association between elevated levels of MASP-2 and NLR with the likelihood of cervical cancer metastasis.

The Significance of NLR in Clinical Practice

The study found that NLR, a marker of inflammation, was closely linked to key aspects of cervical cancer, including stage, histopathology type, tumor size, and metastasis. This discovery is crucial as it suggests that NLR could be a valuable tool for clinicians to assess the risk of cervical cancer metastasis. The simplicity and affordability of measuring NLR make it a practical and accessible option for routine clinical practice.

Balancing the Scales: Understanding Immune System Dynamics

This research sheds light on the complex interplay between the immune system and inflammation in cervical cancer. The discovery that MASP-2, a component of the immune system, is associated with metastasis highlights the importance of understanding immune system dynamics in cancer development. By gaining a deeper understanding of the role of these parameters, clinicians can potentially tailor treatment strategies to address the specific needs of each patient. Remember, maintaining a healthy immune system is crucial for combating diseases like cancer. So, consider incorporating immune-boosting practices into your daily life, such as eating a nutritious diet, getting enough sleep, and managing stress.

Dr. Camel's Conclusion

This study is like a compass guiding us through the intricate landscape of cervical cancer. It emphasizes the crucial role of immune and inflammatory parameters in predicting metastasis and offers a valuable tool - NLR - for clinical practice. We need to continue our exploration of these parameters and understand their complex interactions with the immune system in various diseases. Like the camel navigating the vast desert, we must be persistent in our quest for knowledge and understanding, always seeking new pathways towards better health outcomes.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-12-11
Further Info :

Pubmed ID

38073222

DOI: Digital Object Identifier

PMC10711526

Related Literature

SNS
PICO Info
in preparation
Languages

English

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