Paper Details 
Original Abstract of the Article :
We designed this investigation to assess the occurrence of systemic beta adrenergic side effects associated with the inhalation of an increased dose of the beta2 receptor agonist albuterol. Since therapeutic aerosols delivered by metered dose inhaler (MDI) are preferentially deposited in the mouth a...See full text at original site
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引用元:
https://doi.org/10.1378/chest.91.3.382

データ提供:米国国立医学図書館(NLM)

Albuterol Inhalation: A Journey Through the Desert of Asthma Treatment

Asthma is a chronic respiratory condition that affects millions worldwide. This study, like a camel traversing the sands of asthma research, investigates the systemic cardiovascular and metabolic effects associated with the inhalation of an increased dose of albuterol, a common medication used to treat asthma. The researchers explored the potential side effects of high-dose albuterol inhalation and the impact of mouth rinsing and gargling on these effects, seeking to optimize treatment strategies for asthma patients.

Albuterol's Systemic Effects: Navigating the Desert of Side Effects

The researchers, like skilled desert navigators, found that high-dose albuterol inhalation led to significant increases in heart rate, serum glucose, and insulin levels, indicating systemic drug absorption. This finding, like a shimmering oasis of knowledge, underscores the importance of carefully considering the potential side effects of high-dose albuterol inhalation, especially for patients with pre-existing cardiovascular or metabolic conditions.

Mouth Rinsing and Gargling: A Desert Oasis of Hope?

The researchers, like a caravan seeking a solution to a challenge, investigated the effectiveness of mouth rinsing and gargling in reducing the systemic effects of albuterol. They found that while mouth rinsing and gargling did remove some of the drug, it did not significantly reduce the systemic effects. This finding, like a desert mirage, suggests that mouth rinsing and gargling might not be a reliable strategy for mitigating the systemic effects of albuterol inhalation.

Dr. Camel's Conclusion

This study, like a camel traversing the sands of asthma research, highlights the importance of carefully considering the potential systemic effects of high-dose albuterol inhalation. While albuterol is a valuable medication for treating asthma, it's crucial to be aware of its potential side effects and to discuss any concerns with your doctor. This research, like a well-stocked caravan, provides valuable insights into the complexities of asthma treatment and the importance of individualized care.

Date :
  1. Date Completed 1987-03-30
  2. Date Revised 2019-05-14
Further Info :

Pubmed ID

3816316

DOI: Digital Object Identifier

10.1378/chest.91.3.382

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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