Paper Details
- Home
- Paper Details
Correlation of subjective side effects with plasma concentrations of nortriptyline.
Author: AsbergM, CronholmB, SjöqvistF, TuckD
Original Abstract of the Article :
Plasma levels of tricyclic antidepressant drugs vary considerably between individuals receiving the same amount of drug. The bearing of this variation on the occurrence of subjective side effects was investigated in 40 psychiatric inpatients with depressive disorders. Plasma levels were determined b...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1136/bmj.4.5726.18
データ提供:米国国立医学図書館(NLM)
Nortriptyline: A Look at its Plasma Levels and Side Effects
The [pharmacology] of medications is a complex landscape, and understanding how drugs interact with the body is crucial for effective treatment. This study, like a careful explorer navigating a vast desert of chemical compounds, investigates the relationship between [nortriptyline] plasma levels and subjective side effects.
Plasma Levels and Side Effects: A Complex Relationship
The researchers discovered that plasma levels of nortriptyline varied considerably between patients, even when they received the same dosage. They also found that side effects were more pronounced at higher plasma levels. This is like a mirage in the desert, where appearances can be deceiving. The study highlights the importance of individualizing treatment approaches to optimize drug efficacy and minimize side effects.
Personalized Approaches to Medication Management
This study emphasizes the need to consider individual variations when administering medication. By monitoring plasma levels and adjusting dosage accordingly, we can optimize treatment effectiveness and minimize the risk of adverse effects. It's a reminder that the journey through the desert of pharmacology requires careful navigation and an understanding of individual needs.
Dr.Camel's Conclusion
This study provides valuable insights into the complexities of nortriptyline treatment. By understanding the relationship between plasma levels and side effects, we can personalize treatment approaches and ensure safer and more effective care for patients. It's a reminder that the journey through the desert of medicine requires careful attention to detail and a willingness to adapt to individual needs.
Date :
- Date Completed 1970-12-02
- Date Revised 2019-05-01
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.