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Combination therapy for multiple myeloma.

Author: AlexanianR, BonnetJ, GehanE, HautA, SalmonS, WeickJ

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

A study of 462 patients with multiple myeloma found that drug combinations including vincristine given at 3-week intervals were associated with higher response rates and longer survival times. Maintenance therapy with azathioprine-prednisone or melphalan-cyclophosphamide-carmustine-prednisone did not prolong survival.
Paper Details　
Original Abstract of the Article :
The effect of six different chemotherapy regimens were evaluated in 462 previously untreated patients with multiple myeloma. In comparison with other treatments, drug combinations that included vincristine and were given at 3-week intervals were associated with higher response rates and longer survi...See full text at original site
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引用元：
https://doi.org/10.1002/1097-0142(197712)40:6<2765::aid-cncr2820400602>3.0.co;2-x

データ提供：米国国立医学図書館（NLM）

Combating Multiple Myeloma: Finding the Right Cocktail

Multiple myeloma, a cancer of plasma cells, is a challenging disease to treat. This study investigated the effectiveness of various chemotherapy regimens in combating this disease. The researchers, like skilled bartenders crafting the perfect cocktail, explored the combinations of different drugs to find the most effective treatment. They meticulously analyzed the results of different treatment strategies, seeking the best approach to combat this formidable foe.

A Winning Combination for Combating Myeloma

The study found that [combinations of drugs including vincristine] were associated with higher response rates and longer survival times for patients with multiple myeloma. This finding highlights the importance of strategic drug combinations in maximizing treatment effectiveness and improving patient outcomes. Like a skilled desert traveler using diverse resources to survive, researchers have discovered a winning formula for combating this challenging disease.

A New Hope for Multiple Myeloma Patients

The study offers a valuable roadmap for treating multiple myeloma, emphasizing the importance of selecting the right combination of drugs. This finding could lead to improved treatment strategies and greater hope for patients battling this complex disease. It's like finding a hidden oasis in the vast desert of cancer research - a promising path toward more effective treatment options and better outcomes for patients.

Dr. Camel's Conclusion

This study underscores the importance of finding the right combination of drugs for treating multiple myeloma. Like a skilled alchemist blending ingredients to create a powerful elixir, researchers have discovered that a strategic cocktail of drugs can significantly improve patient outcomes. This research offers a beacon of hope in the fight against this challenging disease.

Date :
  1. Date Completed 1978-02-23
  2. Date Revised 2019-06-19
Further Info :

Pubmed ID

589554

DOI: Digital Object Identifier

10.1002/1097-0142(197712)40:6<2765::aid-cncr2820400602>3.0.co;2-x

Related Literature

Article Analysis
・Effective treatment of multiple myeloma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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