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The hypotensive activity and side effects of methyldopa, clonidine, and guanfacine.
Author: ThoolenM J, TimmermansP B, van ZwietenP A
Original Abstract of the Article :
Clonidine (Catapres, Catapresan), guanfacine (Estulic), and methyldopa (Aldomet) are the prototypes of centrally acting antihypertensive drugs. Clonidine and guanfacine are lipophilic drugs that readily penetrate into the brain, where they stimulate alpha-adrenergic receptors in the pontomedullary r...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1161/01.hyp.6.5_pt_2.ii28
データ提供:米国国立医学図書館(NLM)
Centrally Acting Antihypertensive Drugs: A Journey Through the Nervous System
The field of [hypertension treatment] is as vast and complex as the desert itself. This research delves into the mechanisms of action of [centrally acting antihypertensive drugs] such as [methyldopa, clonidine, and guanfacine]. The authors explain how these medications work by [targeting specific receptors in the brain] to [reduce peripheral sympathetic tone] and [lower blood pressure]. This research provides valuable insights into the [neurological pathways] involved in regulating blood pressure and the potential side effects associated with these medications.
Understanding the Mechanisms of Action of Antihypertensive Drugs
This research sheds light on the [complex interplay] between the nervous system and blood pressure regulation. The study highlights how [different medications] can affect these pathways and potentially [induce side effects].
Navigating the Landscape of Hypertension Treatment
This research underscores the importance of [working closely with your healthcare provider] to find the most appropriate treatment for your unique situation. It also highlights the need for [open communication] to address any potential side effects that you may experience.
Dr. Camel's Conclusion
This study, like a camel caravan navigating the desert, takes us on a journey through the complex mechanisms of action of centrally acting antihypertensive drugs. The research highlights the [importance of understanding] these mechanisms to ensure safe and effective treatment.
Date :
- Date Completed 1984-12-28
- Date Revised 2019-07-22
Further Info :
Related Literature
English
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