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[Electroencephalographically determined sedative effects (vigilosomnography) of the new Thienodiazepin-derivate clotiazepam (author's transl)].

Author: AufdembrinkeB, KuglerJ, LaubM, RodeC P

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Both diazepam and clotiazepam demonstrated sedative effects, with clotiazepam producing slightly stronger sedation than diazepam. Clotiazepam, however, was associated with fewer side effects than diazepam.
Paper Details　
Original Abstract of the Article :
In a double blind, randomized clinical study eighteen volunteers received either placebo or 5 mg diazepam or 5 mg clotiazepam at three different times at an interval of one week. Beside other parameters which have been measured a 60-minute polygraphic EEG recording was made thirty minutes after admi...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/6117459

データ提供：米国国立医学図書館（NLM）

Clotiazepam: A Gentle Sedative for a Restful Night

This study explores the world of [pharmacology and sleep medicine], specifically examining the sedative effects of clotiazepam, a new medication belonging to the thienodiazepine class of drugs. The researchers compared the effects of clotiazepam to placebo and diazepam, another commonly used sedative, in a group of volunteers. They found that clotiazepam, at a dose of 5 mg, had a similar sedative effect to diazepam but with fewer side effects.

Clotiazepam's Gentle Touch: A Peaceful Oasis in the Desert of Sleeplessness

The study shows that clotiazepam, at a dose of 5 mg, had a similar sedative effect to diazepam but with fewer side effects. It's like finding an oasis in the desert of sleeplessness, where the gentle effects of clotiazepam can help you drift off to a peaceful night's sleep.

Getting a Good Night's Rest: A Journey Through the Desert of Sleep

This research highlights the importance of finding the right medication for sleep disorders, considering both effectiveness and side effects. It's like choosing the right camel for a journey through the desert of sleep: some camels are gentler and more comfortable than others.

Dr.Camel's Conclusion

This study provides valuable information for doctors and patients seeking to improve sleep quality. It's a reminder that a good night's sleep is essential for overall well-being and that there are safe and effective options available to help us achieve restful slumber.

Date :
  1. Date Completed 1982-01-09
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6117459

DOI: Digital Object Identifier

6117459

Related Literature

Article Analysis
・Effects of diazepam
SNS
PICO Info
in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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