Immunogenicity and safety of heat-inactivated hepatitis B vaccine (CLB) in low risk human volunteers and in patients treated with chronic haemodialysis in the Netherlands.

Author: BrummelhuisH G, DeesP J, LelieP N, Reerink-BrongersE E, ReesinkH W, van AkenW G

Paper Details 
Original Abstract of the Article :
The immunogenicity and safety of a heat-inactivated hepatitis B vaccine (HB-vaccine) were studied in healthy human volunteers (n = 471) at a low risk to be infected with hepatitis B virus (HBV) and in patients on chronic haemodialysis (n = 227), who were treated in hepatitis B free centres. After va...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/6228459

データ提供:米国国立医学図書館(NLM)

The Effectiveness and Safety of Hepatitis B Vaccine

Imagine a vast desert, where the heat and dryness can make life difficult. Now imagine a vaccine as a source of cool water, protecting people from a potentially dangerous disease. This study delves into the effectiveness and safety of a heat-inactivated hepatitis B vaccine. Researchers tested the vaccine on two groups of individuals: healthy volunteers and patients on chronic hemodialysis. They wanted to see how well the vaccine protected them from hepatitis B infection and if it caused any unwanted side effects.

The Vaccine's Protective Oasis

The study found that the vaccine was highly effective in both groups, with a significant majority developing antibodies against the hepatitis B virus. The researchers also observed that increasing the dosage of the vaccine for hemodialysis patients further enhanced their immune response. The study also confirmed that the vaccine had a very good safety profile with minimal side effects.

Navigating the Desert of Disease Prevention

This study highlights the importance of vaccination in protecting ourselves from infectious diseases. The researchers found that the hepatitis B vaccine is a safe and effective tool for preventing infection, especially for those at risk, like hemodialysis patients. This study reinforces the message that vaccination is a vital step in staying healthy and protecting ourselves from the harsh realities of infectious diseases.

Dr.Camel's Conclusion

The findings of this study are a welcome oasis in the desert of infectious disease prevention. It demonstrates the effectiveness and safety of the hepatitis B vaccine, offering crucial protection against a potentially serious illness. The study reminds us that vaccination is an essential tool for protecting our health and navigating the vast desert of infectious diseases.

Date :
  1. Date Completed 1984-02-24
  2. Date Revised 2008-11-21
Further Info :

Pubmed ID

6228459

DOI: Digital Object Identifier

6228459

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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