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Efficacy trial of heat-inactivated hepatitis B vaccine (CLB) in male homosexuals in the Netherlands.

Author: Albrecht-van LentP, CoutinhoR A, HuismanJ, KuipersH, LelieP N, Reerink-BrongersE E, ReesinkH W, SchutL J, StoutjesdijkL, van AkenW G

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A heat-inactivated hepatitis B vaccine showed a significant protective effect against HBV infection in susceptible homosexual men. The vaccine was well tolerated with no serious side effects.
Paper Details　
Original Abstract of the Article :
The efficacy of a heat-inactivated hepatitis B virus (HBV) vaccine, containing 3 micrograms-HBsAg, was studied among a group of 800 susceptible homosexual men. The trial was conducted randomized, placebo-controlled and double blind. At the trial end point (21.5 months) the attack-rate for all HBV in...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/6228469

データ提供：米国国立医学図書館（NLM）

Protecting Against Hepatitis B: A Vaccine Trial in Homosexual Men

Hepatitis B virus (HBV) infection is a significant health concern, particularly among certain populations. This study focused on the efficacy of a heat-inactivated HBV vaccine in a group of susceptible homosexual men. The researchers conducted a randomized, placebo-controlled, double-blind trial to assess the effectiveness of the vaccine in preventing HBV infection.

The study found that the vaccine was highly effective in preventing HBV infection, demonstrating a significant reduction in attack rates among vaccine recipients. The researchers also observed high seroconversion rates, with a majority of vaccinees developing protective antibody levels. This study provides strong evidence for the efficacy of HBV vaccination in preventing infection, particularly in high-risk populations.

A Beacon of Hope in the Desert of HBV

This study offers a beacon of hope in the ongoing fight against HBV infection, demonstrating the effectiveness of vaccination in protecting high-risk populations. The findings highlight the importance of vaccination programs in reducing the burden of HBV infection and improving global health.

Navigating the Shifting Sands of HBV Infection

Hepatitis B is a challenging disease, but this study offers a path toward a more effective response. The findings underscore the importance of vaccination in preventing HBV infection, particularly in high-risk groups.

Dr. Camel's Conclusion

The threat of HBV infection can feel like a relentless sandstorm. This study offers hope by demonstrating the efficacy of vaccination in protecting individuals from this disease. By understanding the importance of vaccination, we can create a more resilient and healthier world.

Date :
  1. Date Completed 1984-02-24
  2. Date Revised 2008-11-21
Further Info :

Pubmed ID

6228469

DOI: Digital Object Identifier

6228469

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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