Paper Details
- Home
- Paper Details
The effects of antacid and propantheline on the absorption of oral ranitidine.
Author: DonnK H, EshelmanF N, FabreL, PlachetkaJ R, PowellJ R
Original Abstract of the Article :
The effects of propantheline bromide and an aluminum hydroxide/magnesium hydroxide suspension on absorption of ranitidine were evaluated in 12 healthy volunteers according to a Latin square design. Ranitidine 150 mg was administered alone, with 30 ml antacid or preceded by 15 mg propantheline. Ten s...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1002/j.1875-9114.1984.tb03326.x
データ提供:米国国立医学図書館(NLM)
The Impact of Antacids and Propantheline on Ranitidine Absorption
This research delves into the fascinating world of drug interactions. It specifically investigates how common medications like antacids and propantheline affect the absorption of ranitidine, a widely used drug for treating ulcers. The study employed a Latin square design, a clever strategy that helps researchers control for potential biases. They discovered that antacids had no significant impact on ranitidine absorption, but propantheline increased its bioavailability by 22%. While propantheline also tended to increase the maximum ranitidine concentration in the blood and delay its peak, these observations didn't reach statistical significance. This study provides valuable insights into how these medications might interact with each other, which is crucial information for doctors and patients alike.
Propantheline: A Game Changer for Ranitidine?
This research sheds light on the interesting interaction between ranitidine and propantheline. Propantheline actually boosted the amount of ranitidine absorbed by the body. This finding could potentially lead to new strategies for optimizing ranitidine treatment, ensuring maximum effectiveness. It's like adding a little extra fuel to the fire, helping ranitidine work its magic even better!
Ranitidine: Safe for Most, but Watch Out for Propantheline
This research suggests that ranitidine can be safely taken along with antacids. However, it's important to be cautious when combining it with propantheline. Since propantheline can affect ranitidine's absorption, careful monitoring might be necessary. Think of it like mixing different flavors in a delicious dessert - some combinations work beautifully, while others might need a little adjustment. Always consult your doctor for personalized guidance.
Dr.Camel's Conclusion
This study emphasizes the importance of understanding drug interactions. Just like a camel navigating a vast desert, our bodies are complex ecosystems, and medications can have intricate effects on each other. It's essential to consult healthcare professionals to ensure optimal medication choices and prevent any unexpected side effects.
Date :
- Date Completed 1984-06-21
- Date Revised 2019-09-13
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.