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Side effects of phenobarbital and phenytoin during long-term treatment of epilepsy.

Author: IivanainenM, SavolainenH

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Phenobarbital and phenytoin have significant long-term side effects, including sedation, behavioral problems, and neurotoxicity. Phenytoin can lead to cerebellar syndrome, encephalopathy, psychosis, and locomotor dysfunction.
Paper Details　
Original Abstract of the Article :
Phenobarbital and phenytoin have good antiepileptic effect, but clinically significant untoward effects occur during their long-term use. Phenobarbital may cause hyperactivity, behavioral problems, sedation, and even dementia; these effects are dose related to some extent. Side effects of phenytoin ...See full text at original site
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引用元：
https://doi.org/10.1111/j.1600-0404.1983.tb01535.x

データ提供：米国国立医学図書館（NLM）

Understanding the Side Effects of Antiepileptic Medications

Epilepsy is a neurological disorder that can significantly impact a person's life. This research examines the long-term side effects of two commonly used antiepileptic medications, phenobarbital and phenytoin. The study highlights the potential risks associated with these medications, emphasizing the importance of careful monitoring and management.

Navigating the Potential Risks of Antiepileptic Medications

The study found that both phenobarbital and phenytoin, while effective in controlling seizures, can have significant side effects, including behavioral problems, sedation, and even neurotoxicity. The study also highlights the potential for drug interactions, particularly in individuals taking multiple medications.

Making Informed Decisions About Epilepsy Treatment

This research provides valuable insights for healthcare professionals and patients with epilepsy. The study emphasizes the importance of understanding the potential risks and benefits of antiepileptic medications and working closely with a healthcare provider to develop a personalized treatment plan.

Dr. Camel's Conclusion

Treating epilepsy is like navigating a desert with hidden mirages. This study reminds us that even effective medications can have unexpected side effects. Understanding these risks and working with a healthcare provider is crucial for finding a safe and effective path through the challenges of epilepsy.

Date :
  1. Date Completed 1984-05-02
  2. Date Revised 2019-10-31
Further Info :

Pubmed ID

6424397

DOI: Digital Object Identifier

10.1111/j.1600-0404.1983.tb01535.x

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Article Analysis
・Side Effects of phenobarbital
SNS
PICO Info
in preparation
Languages

English

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