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Undesirable side effects of isoniazid and rifampin in largely twice-weekly short-course chemotherapy for tuberculosis.
Author: DuttA K, MoersD, SteadW W
Original Abstract of the Article :
Between January 1976 and June 1981, 814 patients with pulmonary tuberculosis were treated for 9 months with isoniazid (INH) and rifampin (RIF), daily for 1 month and twice weekly for the other 8 months. Overall success was achieved in 95% of the 586 patients who completed therapy: in 15 patients (2....See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1164/arrd.1983.128.3.419
データ提供:米国国立医学図書館(NLM)
Isoniazid and Rifampin: A Camel's Journey Through the Desert of Tuberculosis Treatment
The field of infectious diseases is a vast desert, filled with challenges and uncertainties. This study explores the use of isoniazid (INH) and rifampin (RIF), two drugs used to treat tuberculosis, in a twice-weekly short-course chemotherapy regimen. The researchers analyze data from a large cohort of patients, providing valuable insights into the efficacy and side effects of this treatment approach. These findings are crucial, as they help to guide clinicians in making informed decisions about the best treatment options for their patients.
Isoniazid and Rifampin: A Desert Oasis of Effective Treatment
The study found that the twice-weekly short-course chemotherapy regimen was effective in treating tuberculosis, achieving a high success rate. This is like finding a hidden oasis in the desert, offering relief from the harsh realities of this infectious disease. The study also highlights the importance of careful monitoring for potential side effects, particularly hepatic toxicity and hematologic abnormalities. This is like choosing the right camel for the desert journey, considering both its strengths and limitations.
Isoniazid and Rifampin: A Desert of Knowledge and Challenges
This research underscores the need for continued research and development of new treatments for tuberculosis. It's like exploring a vast desert, where every discovery leads to new questions and challenges. By understanding the efficacy and safety of different tuberculosis treatment regimens, we can continue to refine treatment strategies and improve patient outcomes.
Dr.Camel's Conclusion
This study provides valuable insights into the efficacy and safety of a twice-weekly short-course chemotherapy regimen for treating tuberculosis. It highlights the importance of careful patient monitoring to minimize the risk of side effects and maximize treatment success. As we continue to explore the complex world of infectious diseases, we can use these findings to guide future research and improve patient care.
Date :
- Date Completed 1983-10-28
- Date Revised 2019-10-31
Further Info :
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English
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