Regional cerebral blood flow in parkinsonism. Measurement before and after levodopa.

Author: BentinS, CooperG, LavyS, MelamedE

Paper Details 
Original Abstract of the Article :
Data from recent studies in experimental animals suggest that central dopaminergic mechanisms may be involved in regulation of the regional cerebral blood flow (rCBF) in the mammalian brain. In order to evaluate possible effects of dopaminergic stimulation on human cerebral circulation, rCBF was mea...See full text at original site
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引用元:
https://doi.org/10.1016/0022-510x(78)90144-2

データ提供:米国国立医学図書館(NLM)

Exploring the Brain's Blood Flow in Parkinson's Disease

This study delves into the intricate world of Parkinson's disease, a neurological disorder that affects movement and coordination. The researchers examined the impact of levodopa, a medication used to treat Parkinson's disease, on regional cerebral blood flow (rCBF).

A Deeper Understanding of Parkinson's

The study found that chronic levodopa treatment did not significantly alter rCBF in patients with Parkinson's disease. This finding suggests that the dopaminergic system, which is affected by Parkinson's disease, may not play a major role in regulating blood flow to the brain. It's like examining the intricate network of water channels in a desert oasis, searching for clues to understand the dynamics of the ecosystem.

Navigating the Desert of Parkinson's Research

This research offers valuable insights into the complex neurological processes involved in Parkinson's disease. While the study did not find a direct link between levodopa and rCBF changes, it lays the groundwork for further exploration of the intricate relationship between the brain's blood flow and Parkinson's disease.

Dr.Camel's Conclusion

This research journey into the desert of Parkinson's disease reveals that there is still much to discover about the complex interplay of neurological processes. The findings may not offer a definitive answer, but they pave the way for further exploration and understanding, bringing us closer to finding effective treatments for this debilitating disease.

Date :
  1. Date Completed 1979-03-24
  2. Date Revised 2019-07-24
Further Info :

Pubmed ID

731264

DOI: Digital Object Identifier

10.1016/0022-510x(78)90144-2

Related Literature

SNS
PICO Info
in preparation
Languages

English

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