[Relation of dose, serum concentration and side effects in intravenous aminophylline therapy].

Aminophylline Therapy: A Careful Journey Through the Desert

Intravenous aminophylline therapy, a treatment commonly used for chronic obstructive bronchitis, requires careful navigation like a journey through a vast and unforgiving desert. This study explores the relationship between aminophylline dose, serum concentration, and side effects in hospitalized patients. The authors meticulously monitored serum theophylline levels, like charting a course through the desert, to determine the optimal therapeutic range and identify potential risks.

Navigating the Sands of Theophylline Toxicity

The findings revealed that maintaining theophylline serum concentrations within the optimal range is crucial for minimizing side effects. The authors discovered that the incidence of side effects was directly linked to theophylline serum concentration, like encountering a treacherous sandstorm in the desert. They identified elderly patients with cardiac failure as being particularly susceptible to theophylline toxicity, highlighting the importance of individualized dosage adjustments.

The Oasis of Personalized Therapy

This study emphasizes the importance of personalized medicine, like finding a hidden oasis in the desert. It underscores the need for careful monitoring and dosage adjustments based on individual patient factors, like carefully choosing the safest and most effective path through the desert. The research highlights the critical role of monitoring serum theophylline levels to ensure optimal treatment outcomes and minimize the risk of toxicity.

Dr. Camel's Conclusion

This study serves as a valuable guide for clinicians navigating the terrain of aminophylline therapy. By carefully monitoring serum theophylline levels and adjusting dosages as needed, healthcare providers can ensure safe and effective treatment for patients with chronic obstructive bronchitis. Like a skilled desert navigator, clinicians can use the insights from this research to chart a course that minimizes risks and maximizes therapeutic benefit for their patients.