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[On the question of endocrine side effects in patients on medication for renal calcium stone disease (author's transl)].
Author: DöringB, MinneH, RussmannD, UhlK, ZieglerR
Original Abstract of the Article :
In patients with recurrent idiopathic nephrolithiasis we studied whether treatment with sodium cellulose phosphate leading to decreased intestinal calcium absorption could induce secondary hyperparathyroidism and whether thiazides which diminish calciuria would impair glucose tolerance. After remova...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/7414768
データ提供:米国国立医学図書館(NLM)
Endocrine Side Effects of Medications for Renal Calcium Stone Disease
This study investigates the potential endocrine side effects of medications used to treat renal calcium stone disease. The researchers examined the effects of sodium cellulose phosphate and thiazides on parathyroid hormone levels and glucose tolerance, respectively. They recruited 74 patients with recurrent kidney stones and assigned them to three treatment groups: conventional therapy, sodium cellulose phosphate, and sodium cellulose phosphate plus hydrochlorothiazide. The study found no evidence of secondary hyperparathyroidism in patients receiving either sodium cellulose phosphate or the combination therapy. Additionally, hydrochlorothiazide did not worsen glucose tolerance in the patients treated with this combination.
Navigating the Desert of Kidney Stone Treatment: A Safe and Effective Approach
This research provides reassurance regarding the safety of sodium cellulose phosphate and thiazide therapy for renal calcium stone disease. The study found no evidence of significant endocrine side effects, suggesting that these medications can be used without causing harm. However, it's important to note that the study duration was relatively short (one year). Further research is needed to investigate the long-term effects of these medications and to assess their efficacy in preventing stone recurrence.
Finding the Right Path in the Desert of Kidney Health: A Journey of Discovery
This study emphasizes the importance of carefully considering the potential side effects of medications, even those intended for specific conditions. It's like navigating a vast desert; you need to be aware of the potential hazards and choose your path wisely. While the results suggest that sodium cellulose phosphate and thiazides are generally safe, further research is crucial to ensure their long-term safety and efficacy. This study encourages a continuous exploration of treatment options and a commitment to patient well-being.
Dr.Camel's Conclusion
This study explores the potential endocrine side effects of medications used to treat kidney stones. The research found no evidence of significant side effects, suggesting that these medications can be used safely. However, further research is needed to evaluate the long-term effects and to optimize treatment strategies for kidney stone disease. It's like navigating a vast desert; finding the right path requires careful consideration and ongoing exploration to ensure optimal outcomes.
Date :
- Date Completed 1980-11-20
- Date Revised 2013-11-21
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