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Controlled clinical study of naltrexone side effects comparing first-day doses and maintenance regimens.

Author: BrahenL S, CaponeT, HellerR C, LandyH J, LewisM J, LindenS L

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Naltrexone was found to have minimal side effects, with the least number of patients reporting side effects daily in the group receiving three doses per week.
Paper Details　
Original Abstract of the Article :
In a controlled double-blind clinical study, 42 patients reported side effects and severity of side effects to naltrexone on three different first-day doses and maintenance dosage regimens. Initiating doses of 25, 100, and 150 mg were administered. The maintenance regimens involved 350 mg of naltrex...See full text at original site
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引用元：
https://doi.org/10.3109/00952997809028001

データ提供：米国国立医学図書館（NLM）

Naltrexone Side Effects: Comparing First-Day Doses and Maintenance Regimens

The use of medications, especially those used for addiction treatment, requires a careful understanding of their side effects. This study investigates the side effects of naltrexone, a medication used in opioid addiction treatment, comparing the effects of different first-day doses and maintenance regimens. This research, like a desert traveler testing different routes for their caravan, seeks to determine the optimal dosing strategy for naltrexone, minimizing side effects and maximizing therapeutic benefits.

Naltrexone Side Effects: A Comparison of Dosing Strategies

The study compares the side effects of naltrexone across different first-day doses and maintenance regimens, seeking to identify the strategy with the most favorable side effect profile. This research, like a desert gardener carefully studying the effects of different irrigation methods, provides insights into the optimal dosing strategy for naltrexone, ensuring patient comfort and adherence to treatment.

Naltrexone Side Effects: A Guide for Effective and Safe Treatment

This study provides valuable insights into the side effects of naltrexone, guiding clinicians in selecting the most appropriate dosing strategy for each patient. The study highlights the importance of individualizing treatment, taking into account the unique needs and characteristics of each patient. This research, like a desert guide navigating a complex terrain, provides valuable information for ensuring the safe and effective use of naltrexone in opioid addiction treatment.

Dr.Camel's Conclusion

This study provides valuable insights into the side effects of naltrexone, comparing the effects of different first-day doses and maintenance regimens. The findings highlight the importance of individualizing treatment, considering the unique needs of each patient to minimize side effects and optimize treatment outcomes.

Date :
  1. Date Completed 1979-05-26
  2. Date Revised 2019-09-18
Further Info :

Pubmed ID

747177

DOI: Digital Object Identifier

10.3109/00952997809028001

Related Literature

Article Analysis
・Side Effects of naltrexone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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