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Felbamate monotherapy: implications for antiepileptic drug development.

Author: AlbertP, FlaminiR, KetterT, KoD, MalowB, StertzB, TheodoreW H, WhiteS

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study investigated the effect of felbamate monotherapy on seizure rate in patients with partial and secondarily generalized seizures. Felbamate significantly reduced seizure frequency, but side effects were common, leading to premature discontinuation in some patients.
Paper Details　
Original Abstract of the Article :
We studied the effect of felbamate (FBM) monotherapy on seizure rate in patients with partial and secondarily generalized seizures undergoing presurgical monitoring at a single site. The study design was a double-blind placebo-controlled parallel monotherapy trial. Forty patients whose seizures had ...See full text at original site
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引用元：
https://doi.org/10.1111/j.1528-1157.1995.tb00468.x

データ提供：米国国立医学図書館（NLM）

Felbamate: A Potential Breakthrough for Epilepsy Treatment

This study explores the potential of felbamate (FBM) as a treatment for epilepsy. The researchers conducted a double-blind placebo-controlled trial to assess FBM's effectiveness in reducing seizure frequency. The study found that FBM significantly reduced seizure rates compared to placebo. While the study also reported some side effects, the researchers concluded that FBM shows promise as a monotherapy treatment for epilepsy.

Felbamate's Potential in Epilepsy Management

The study provides strong evidence for the effectiveness of felbamate in reducing seizure frequency in patients with epilepsy. This finding has important implications for the management of this neurological disorder.

Living with Epilepsy: Dr. Camel's Advice

Imagine a camel navigating a desert with shifting sands - it requires adaptability and resilience. Similarly, living with epilepsy can be a challenging journey. It's crucial to consult with your doctor to find the best treatment options for your specific situation.

Dr. Camel's Conclusion

This research sheds light on the potential of felbamate as a valuable treatment option for epilepsy. The study's results provide hope for patients battling this complex neurological condition. As Dr. Camel, I believe that advancements in medicine are essential for improving the lives of those living with epilepsy. Remember, like a camel adapting to the harsh desert environment, we can find ways to navigate the challenges of epilepsy and live fulfilling lives.

Date :
  1. Date Completed 1995-11-30
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

7588454

DOI: Digital Object Identifier

10.1111/j.1528-1157.1995.tb00468.x

Related Literature

Article Analysis
・Side Effects of felbamate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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