Efficacy and safety of benazepril plus hydrochlorothiazide versus benazepril alone in hypertensive patients unresponsive to benazepril monotherapy.

Author: HolwerdaK, HoogmaR P, HuigeR C, OldenbroekC, RijnierseJ M, WesterA

Paper Details 
Original Abstract of the Article :
A combination of benazepril 10 mg plus hydrochlorothiazide 12.5 mg once daily was investigated in the treatment of patients with mild-to-moderate essential hypertension who had not responded to monotherapy with benazepril 10 mg. Patients failing to respond to 4 weeks of benazepril 10 mg/d were rando...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/7697691

データ提供:米国国立医学図書館(NLM)

Benazepril Plus Hydrochlorothiazide: A Powerful Duo for Resistant Hypertension

The battle against [hypertension] can feel like a relentless trek through a desert of high blood pressure, requiring persistent effort and careful navigation. This research explores the effectiveness of combining [benazepril] and [hydrochlorothiazide] for treating patients with [resistant hypertension] who have not responded to [benazepril monotherapy]. The study aimed to compare the [blood pressure lowering effects] of this combination therapy to [benazepril alone].

A New Strategy in the Desert of Resistant Hypertension

The study found that [benazepril plus hydrochlorothiazide] led to [significantly greater reductions] in [blood pressure] compared to [benazepril monotherapy]. The combination therapy also resulted in a [lower incidence] of [adverse events], particularly [cough]. These findings suggest that combining these medications may be a [more effective] and [better tolerated] approach for managing [resistant hypertension].

Finding a Path to Lower Blood Pressure

This research offers a promising new strategy for managing [resistant hypertension]. The combination of [benazepril] and [hydrochlorothiazide] has the potential to [improve blood pressure control] while minimizing [side effects]. Further research is needed to explore the long-term efficacy and safety of this approach in a wider patient population.

Dr.Camel's Conclusion

Just as a camel must find a way to navigate the harsh desert landscape, patients with resistant hypertension often face a challenging journey to achieve optimal blood pressure control. This research offers a beacon of hope by demonstrating the potential of a combined therapy to provide more effective and tolerable treatment options. It's a testament to the ongoing search for innovative solutions in the field of cardiovascular health.

Date :
  1. Date Completed 1995-05-02
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

7697691

DOI: Digital Object Identifier

7697691

Related Literature

SNS
PICO Info
in preparation
Languages

English

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