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Efficacy and safety of benazepril plus hydrochlorothiazide versus benazepril alone in hypertensive patients unresponsive to benazepril monotherapy.
Author: HolwerdaK, HoogmaR P, HuigeR C, OldenbroekC, RijnierseJ M, WesterA
Original Abstract of the Article :
A combination of benazepril 10 mg plus hydrochlorothiazide 12.5 mg once daily was investigated in the treatment of patients with mild-to-moderate essential hypertension who had not responded to monotherapy with benazepril 10 mg. Patients failing to respond to 4 weeks of benazepril 10 mg/d were rando...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/7697691
データ提供:米国国立医学図書館(NLM)
Benazepril Plus Hydrochlorothiazide: A Powerful Duo for Resistant Hypertension
The battle against [hypertension] can feel like a relentless trek through a desert of high blood pressure, requiring persistent effort and careful navigation. This research explores the effectiveness of combining [benazepril] and [hydrochlorothiazide] for treating patients with [resistant hypertension] who have not responded to [benazepril monotherapy]. The study aimed to compare the [blood pressure lowering effects] of this combination therapy to [benazepril alone].
A New Strategy in the Desert of Resistant Hypertension
The study found that [benazepril plus hydrochlorothiazide] led to [significantly greater reductions] in [blood pressure] compared to [benazepril monotherapy]. The combination therapy also resulted in a [lower incidence] of [adverse events], particularly [cough]. These findings suggest that combining these medications may be a [more effective] and [better tolerated] approach for managing [resistant hypertension].
Finding a Path to Lower Blood Pressure
This research offers a promising new strategy for managing [resistant hypertension]. The combination of [benazepril] and [hydrochlorothiazide] has the potential to [improve blood pressure control] while minimizing [side effects]. Further research is needed to explore the long-term efficacy and safety of this approach in a wider patient population.
Dr.Camel's Conclusion
Just as a camel must find a way to navigate the harsh desert landscape, patients with resistant hypertension often face a challenging journey to achieve optimal blood pressure control. This research offers a beacon of hope by demonstrating the potential of a combined therapy to provide more effective and tolerable treatment options. It's a testament to the ongoing search for innovative solutions in the field of cardiovascular health.
Date :
- Date Completed 1995-05-02
- Date Revised 2013-11-21
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English
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