Anxiolytics' effects on the actual driving performance of patients and healthy volunteers in a standardized test. An integration of three studies.

Author: O'HanlonJ F, SwijgmanH F, UiterwijkM M, VermeerenA, van VeggelL M

Paper Details 
Original Abstract of the Article :
Effects of benzodiazepine (diazepam, lorazepam) and benzodiazepine-like anxiolytics (alpidem, suriclone) and a 5-HT-3 antagonist (ondansetron) on actual driving performance were measured in three double-blind, placebo-controlled studies. Subjects were healthy volunteers in two and anxious patients i...See full text at original site
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引用元:
https://doi.org/10.1159/000119177

データ提供:米国国立医学図書館(NLM)

Anxiolytics' Effects on Driving Performance

This study investigates the impact of

anxiolytics

on driving performance, examining the effects of different types of medications, including benzodiazepines, benzodiazepine-like anxiolytics, and a 5-HT-3 antagonist. The researchers conducted three double-blind, placebo-controlled studies, including both healthy volunteers and patients with anxiety disorders. The results showed that benzodiazepine and benzodiazepine-like anxiolytics consistently produced significant and pervasive driving impairment throughout the treatment period. In contrast, the 5-HT-3 antagonist ondansetron did not impair driving performance. These findings highlight the importance of considering the potential effects of anxiolytics on driving safety.

The Impact of Anxiolytics on Driving Ability

This study demonstrates the substantial impairment that benzodiazepines and benzodiazepine-like anxiolytics can have on driving performance. The researchers found that these medications can significantly reduce driving skills, raising concerns about driving safety. This finding emphasizes the importance of informing patients about the potential side effects of these medications, particularly regarding driving.

Driving Safety Considerations

This study underscores the importance of driving safety when taking anxiolytics. Patients taking benzodiazepines or benzodiazepine-like anxiolytics should be advised to avoid driving until the effects of the medication have subsided. It is also essential for healthcare providers to discuss driving safety considerations with patients, ensuring they understand the potential risks associated with these medications.

Dr.Camel's Conclusion

Imagine navigating a vast desert with a fogged-up windshield. That's what driving under the influence of benzodiazepines and benzodiazepine-like anxiolytics can feel like. This study emphasizes the importance of being mindful of medication effects and prioritizing safety on the road.

Date :
  1. Date Completed 1995-06-28
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

7760989

DOI: Digital Object Identifier

10.1159/000119177

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Languages

English

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