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[The effect of H2-receptor blockers (cimetidine and ranitidin) on parotid gland secretion and salivary carbonic anhydrase activity in the rat].

Author: BorosI, KeszlerP, PóschE, SzombathD

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study found that the H2-receptor antagonists cimetidine and ranitidine, known for their use in treating ulcers, significantly increased parotid secretion in response to bethanechol, a cholinergic stimulant. This suggests that combining bethanechol with these blockers could improve esophageal clearance, potentially benefiting patients with gastroesophageal reflux disease.
Paper Details　
Original Abstract of the Article :
It has been demonstrated, that the H2-receptor antagonists: cimetidine and ranitidine-administered in doses of the same order of magnitude as reported for the inhibition of rat gastric secretion and development of the experimentally induced gastric and duodenal ulcer-are capable of increasing signif...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/7902302

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 1994-01-04
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

7902302

DOI: Digital Object Identifier

7902302

SNS
PICO Info
in preparation
Languages

Hungarian

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