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[Multicenter comparative study of the effects of benazepril and captopril in mild and moderate systemic hypertension].

Author: AlmeidaF A, CarvalhoJ G, MansurA de P, RamiresJ A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Benazepril (BZ) was found to be superior to captopril (CPT) in treating patients with mild or moderate systemic arterial hypertension (SAH). The study involved 174 patients, mean age of 52 +/- 9 years. Both drugs reduced systolic and diastolic blood pressure, but BZ resulted in a better response to treatment.
Paper Details　
Original Abstract of the Article :
PURPOSE: To evaluate the efficacy and safety of benazepril versus captopril in patients with mild or moderate systemic arterial hypertension (SAH). METHODS: A multicenter, double-blind, randomized trial analyzed 174 patients, mean age of 52 +/- 9 years, 68 (39%) men. After 2 weeks under placebo, 90...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8204074

データ提供：米国国立医学図書館（NLM）

Benazepril vs. Captopril: A Comparative Study in Hypertension

Hypertension, or high blood pressure, is a significant health concern, much like a sandstorm threatening a desert traveler's journey. This study compared the efficacy and safety of benazepril and captopril, two medications commonly used to treat hypertension, in patients with mild to moderate systemic arterial hypertension. The researchers aimed to determine the relative effectiveness of these medications in controlling blood pressure.

Benazepril: A More Effective Option for Mild to Moderate Hypertension

The study found that benazepril was more effective than captopril in reducing blood pressure in patients with mild to moderate hypertension. The researchers observed a greater reduction in both systolic and diastolic blood pressure with benazepril compared to captopril. These findings suggest that benazepril could be a more effective treatment option for this range of hypertension.

Managing Blood Pressure: A Vital Component of Health

Hypertension, like a steady stream of desert winds, can gradually erode the body's health. The study emphasizes the importance of effective blood pressure management in reducing cardiovascular risks. The findings suggest that benazepril could be a more effective option for managing mild to moderate hypertension compared to captopril.

Dr.Camel's Conclusion

This research offers valuable insights into the comparative effectiveness of benazepril and captopril in treating mild to moderate hypertension. The findings suggest that benazepril could be a more effective option for controlling blood pressure in this specific population.

Date :
  1. Date Completed 1994-07-05
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8204074

DOI: Digital Object Identifier

8204074

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Languages

Portuguese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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